Research Assistant in Developmental Morphogenesis
We are searching for an outstanding researcher to join the Buckley Lab within the Division of Molecular & Cellular Function at the University of Manchester. Start date from 1st March 2026 (flexible), funded for 1 year initially. Interviews are likely to be held between 5th and 16th January online via Teams.
Background
The Buckley group strives to understand how mechanics and biochemical signaling work together to shape epithelial organs during morphogenesis. Our long‑term goal is to identify mechanisms by which dysregulation of this balance contributes to congenital diseases. We are currently interested in the links between the primary cilium, cell‑cell adhesion, and cellular mechanics during vertebrate secondary neurulation. We have recently developed in vivo optogenetic approaches to image and manipulate cellular mechanics or signaling at sub‑cellular scale deep within the zebrafish brain.
Role Description
The successful candidate will contribute to cutting‑edge optogenetic, live imaging, and quantitative analysis approaches to understand how mechanics and biochemical signaling coordinate to shape epithelial organs, with a focus on the primary cilium. Responsibilities include:
* Assist with optogenetic experiments, live imaging, and analysis of zebrafish models.
* Help run the laboratory and provide training to junior staff.
* Develop a more independent research project, potentially forming the basis for a PhD proposal.
Applicants are encouraged to contact Clare Buckley directly to discuss research interests.
Person Specification
Applicants should be passionate about research with previous lab experience in developmental morphogenesis, epithelial biology, biophysics, or mechanobiology and hold a degree or master’s in a relevant subject. Experience in quantitative image analysis, modeling, zebrafish, or cilium biology is advantageous. Desired qualities include a professional, organized, collaborative work ethos and a willingness to develop creative approaches to challenging research problems.
Application Process
For full details and application process, visit https://www.jobs.manchester.ac.uk/Job/JobDetail?isPreview=Yes&jobid=33787&advert=external.
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