Location of role Oxford, UK Department Proteomics Key Responsibilities Purpose of the role We have an opportunity in our Research Group for a 12-month placement (Year in industry). We are looking for enthusiastic and highly motivated individuals who would relish the chance to learn from Immunocore’s cutting edge science and corporate growth. Immunocore’s ImmTAX technology targets peptides presented by HLA complexes (pHLA) on the cell surface. Mass spectrometry (MS) remains the only direct method to identify and quantify these pHLA targets. However, the limited availability of clinical sample material poses a significant challenge for MS-based analysis, especially in the context of informing patient selection and understanding the mechanism of target pHLA presentation i.e. protein expression to degradation to cell surface presentation. We aim to deepen our understanding of this process by quantifying both the absolute levels of target pHLA and the proteins involved in the pHLA presentation machinery, as well as the source proteins from which these targets originate in different biological models such as cell lines, patient derived xenografts (PDX), and tumour samples. By integrating these datasets, we aim to establish predictive relationships to support translational decision-making in clinical contexts. Key Responsibilities Receive training/mentorship and develop a set of skills (such as: sample preparation, mass spectrometry, data analysis) that will allow identification and absolute quantification of pHLA, and proteins using mass spectrometry based techniques. Grow relevant cell lines and process complex biological systems such as PDX and tumour samples to conduct immunopeptidomics and proteomics experiments for identification and quantification of HLA peptides, and proteins. Analyse mass spectrometry data using bioinformatics tools developed in house and state of the art software to uncover biology and develop the predictive tools for pHLA presentation. Develop deep understanding of related scientific literature. Education & Qualifications Undertaking (currently in second year and looking for a year in industry) BSc. in either Chemical, Biological or Biomedical Sciences with an analytical chemistry, biochemistry or immunology component. What will you receive? Join Immunocore for a paid placement and gain insights from our innovative science and corporate growth. You’ll enjoy 25 days of annual leave (pro rata), pension scheme eligibility, and access to our active Sports and Social Club with subsidized events. Please note this is a full-time position is based at our Abingdon, Oxfordshire office and contracted through a third party. Important information for all applicants The application deadline is 09th January 2026, with phone interviews starting shortly after. Shortlisted candidates will be invited to an in-person Assessment Centre on 23rd, 24th, 25th, or 26th February 2026, providing an opportunity to meet current placement students, learn about the role, and socialize with employees. Placements are expected to begin on 7th September 2026. Please note - should you not be available on all the above dates, unfortunately, we won't be able to proceed with your application. If interested, apply with your CV and a cover letter (combined in one document) stating your main areas of interest. About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions. Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.