Location of role Oxford, UK
Department CMC
Key Responsibilities
Purpose of the role
This role will lead the development of a comprehensive charge profiling knowledge base for ImmTAX molecules, enabling faster, more reliable decision making across the product lifecycle. You will design and execute charge profiling studies using anion exchange chromatography and capillary-based methods and work closely with mass spectrometry specialists to assign major peaks and link charge variants to specific molecular changes. By building and curating a robust database of ImmTAX charge profiles, you will improve understanding of product identity, purity and stability, reduce ambiguity when profiles change, and help streamline program timelines, reduce rework, and lower overall development costs.
Key Responsibilities
You will perform both lab-based and desk-based research using a range of analytical tools. Your responsibilities are expected to include:
Establish a library of ImmTAX and related molecules that require charge profile characterisation.
Select a shortlist of molecules for detailed investigation, based on scientific and program risk.
Optimisation of capillary-based charge profiling methods to improve separation and resolution of key peaks.
Development of fractionation methods to isolate specific charge variants for selected molecules.
Preparing and analysing isolated fractions, including reinjection using standard charge profiling methods to confirm peak identity.
Further characterisation of peaks using extended analytical techniques, such as mass spectrometry.
Time permitting: Development of an automated sample preparation method to increase throughput and reproducibility.
You will receive training and day-to-day support from experienced scientists, with the opportunity to develop practical laboratory skills, data analysis capabilities, and an understanding of biopharmaceutical characterisation.
Education & Qualifications
Currently enrolled in a Bachelor’s degree program and seeking a Year-in-Industry placement in one of the following disciplines:
Pharmaceutical Sciences
Biochemistry
Biotechnology
Chemical Engineering
Physical Chemistry
Or a related scientific field
What will you receive?
Join Immunocore for a paid placement and gain insights from our innovative science and corporate growth. You’ll enjoy 25 days of annual leave (pro rata), pension scheme eligibility, and access to our active Sports and Social Club with subsidized events.
Please note this is a full-time position is based at our Abingdon, Oxfordshire office and contracted through a third party.
Important information for all applicants
The application deadline is 09th January 2026, with phone interviews starting shortly after. Shortlisted candidates will be invited to an in-person Assessment Centre on 23rd, 24th, 25th, or 26th February 2026, providing an opportunity to meet current placement students, learn about the role, and socialize with employees. Placements are expected to begin on 7th September 2026.
Please only apply if you are currently undergoing a degree with a placement year (sandwich year).
Please note - should you not be available on all the above dates, unfortunately, we won't be able to proceed with your application.
If interested, apply with your CV and a cover letter (combined in one document) stating your main interest.
About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.