Research Fellow (109629-1025) Location University of Warwick Campus, Coventry Department Warwick Medical School - Biomedical Sciences Position Type Fixed Term Duration Fixed term contract until 31st December 2027 Salary £35,608 to £46,049 per annum About the Role For informal enquiries, please contact Anne Straube (Professor) at a.straube@warwick.ac.uk A Wellcome-funded postdoctoral position is available in the Straube lab to investigate how molecular motors dynein and KIF1C organise microtubule arrays and transport intracellular cargoes. The postholder will generate knock-in cell lines in iPSCs, differentiate into neurons and other suitable lineages and use live cell imaging and quantitative image analysis to understand microtubule organisation, motor protein conformation and motility. Further, recombinant protein complexes will be prepared and electroporated into cells. The post holder will become a member of the Centre for Mechanochemical Cell Biology and Warwick Medical School benefitting from an outstanding scientific environment and access to state-of-the-art research facilities. Informal enquiries including a CV and motivation statement should be sent to a.straube@warwick.ac.uk. The posts are funded by a Wellcome Investigator Award to investigate how cargo transporters organise the tracks along which they transport cargoes. You will be part of an international, well-resourced team of researchers with access to state-of-the-art equipment (including access to a range of light microscopy systems including spinning disk confocal, TIRF, lattice light sheet and optical tweezers) and a vibrant scientific community with excellent internal and external seminar programmes. About You You will have an excellent first degree in a relevant subject area (biochemistry, cell biology, biological sciences, biophysics etc.), have or expect shortly to complete a PhD or have equivalent research experience. Experience in working on an interdisciplinary scientific project is desirable, strong scientific interest and motivation are essential. For details on the experience and skills required, please refer to the PhD Status If you are near submission of your PhD, or have not yet had it conferred, any offers of employment will be made at Research Assistant level, at the highest spinal point of pay grade 5 (£34,610 per annum). Upon receipt of evidence confirming the successful award of your PhD, you will be promoted to Research Fellow, at the lowest spinal point of grade 6 (£35,608 per annum). About the Department You will join the laboratory of Dr Anne Straube in the Centre for Mechanochemical Cell Biology. The Straube lab aims to understand how intracellular transport is coordinated and microtubule arrays are organised to support cell polarity. In this research programme, we use in vitro reconstitution experiments, single molecule force measurements, quantitative image analysis tools and live cell imaging to understand the function of motor proteins in organising microtubules and transporting cargo. We offer an outstanding environment for discovery science in one of the best universities in the UK. About the University We are a world-leading research-intensive university founded in 1965. We are ranked 67th in the world and 10th in the UK. 92% of our research is rated world-leading or internationally excellent.* Find out more about us on our website.https://warwick.ac.uk/about/ QS World University Rankings 2024, Research Excellence Framework 2021 How to Apply CLOSING DEADLINE: Wednesday 29th October at 23:55 (BST) To apply, please click "Apply" below and submit an application form by the closing deadline. You will be asked to include a CV and a cover letter. Your CV should include: Your education and employment history (including your most recent employment). Any other relevant experience (e.g. volunteering, extracurricular, etc.). Your cover letter should explain: Your motivations for applying to the role. Using examples, how you meet the essential and desirable criteria detailed in the All essential criteria must be met by candidates who are invited to interview. You are welcome to include details of any career breaks (e.g. parental leave, caring responsibilities, sick leave). Interview Date: To be confirmed Start Date: To be confirmed Please note application forms must be submitted before the stated deadline - you will not be able to submit after 23:55 (even if you opened the form earlier). Only applications submitted via our official careers portal (warwick-careers.tal.net) will be considered. What we Offer We provide a comprehensive range of benefits, including: An attractive pension scheme. 30 days holiday plus University Christmas closure. Generous parental/adoption leave policy. Onsite childcare facilities. Excellent learning and development opportunities. We recognise the importance of a healthy work/life balance and offer access to flexible working arrangements. For more information, see here. We are proud to be a Living Wage employer. 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