The University of Sheffield is a remarkable place to work. Our people are at the heart of everything we do. Their diverse backgrounds, abilities and beliefs make Sheffield a world-class university.
We offer a fantastic range of benefits including a highly competitive annual leave entitlement (with the ability to purchase more), a generous pensions scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more. Find out more about our benefits (opens in a new window) and join us to become part of something special.
Overview
We are a dynamic and rapidly developing research group focused on identifying novel therapeutic strategies for amyotrophic lateral sclerosis (ALS). Specifically, we utilise induced pluripotent stem cell-derived motor neurons (iPS-MN) to functionally validate genetic drivers of ALS. We are seeking a motivated Research Assistant to assist with the day-to-day running of the wet lab work and provide technical support for our enthusiastic team of PhD students and Research Associates.
Main Duties And Responsibilities
Maintenance of induced pluripotent stem cells (iPSC), neural progenitor cells, and motor neurons.
Characterisation of cell lines via immunocytochemistry / confocal microscopy, PCR and Western blotting.
Karyotyping and routine mycoplasma testing.
Differentiation of iPSC into motor neurons using our in-house small molecule approach.
Ordering and preparing reagents for the lab to run efficiently.
Maintain accurate records of data.
Assist PhD students / Research Associates with their experiments.
Carry out other duties, commensurate with the grade and remit of the post.
Person Specification
Our diverse community of staff and students recognises the unique abilities, backgrounds, and beliefs of all. We foster a culture where everyone feels they belong and is respected. Even if your past experience doesn't match perfectly with this role's criteria, your contribution is valuable, and we encourage you to apply. Please ensure that you reference the application criteria in the application statement when you apply.
Criteria
Essential Or Desirable
Stage(s) assessed at
Minimum of a Bachelor's degree in a relevant scientific discipline (e.g. biomedical science, neuroscience, biology, biochemistry)
Essential
Application
Experience in stem cell culture
Essential
Application/Interview
Specialised knowledge directly related to neurodegenerative diseases or neuroscience
Essential
Application/Interview
Proficiency in basic and advanced molecular biology methods (e.g., PCR, gel electrophoresis, Western blotting, immunocytochemistry)
Essential
Application/Interview
Demonstrated ability to maintain meticulous and accurate records of data
Essential
Interview
Understanding of ethical and safety guidelines / Biosafety standards for handling biological samples and chemicals
Essential
Interview
Strong interpersonal skills to collaborate effectively with colleagues and supervisors
Desirable
Interview
Proven ability to manage time effectively and prioritize tasks in a fast-paced research environment
Desirable
Interview
Further Information
Grade
6
Salary
£32,080 - £35,608 (pro rata)
Work arrangement
Full-time
Duration
12 months
Line manager
Johnathan Cooper-Knock
Direct reports
Not applicable
Our website
For informal enquiries about this job contact
Tobias Moll, Research Fellow at or on
Next steps in the recruitment process
It is anticipated that the selection process will take place within two weeks of the advert closing. This will consist of an interview and a tour of the labs at SITraN. We plan to let candidates know if they have progressed to the selection stage on the week commencing within one week of the advert closing. If you need any support, equipment or adjustments to enable you to participate in any element of the recruitment process you can contact smph-west-
Our vision and strategic plan
We are the University of Sheffield. This is our vision: (opens in new window).
What We Offer
A minimum of 38 days annual leave including bank holiday and closure days (pro rata) with the ability to purchase more.
Flexible working opportunities, including hybrid working for some roles.
Generous pension scheme.
A wide range of discounts and rewards on shopping, eating out and travel.
A variety of staff networks, providing opportunities for social interaction, peer support and personal development (for example, Race Equality, LGBT+, Women's and Parent's networks).
Recognition Awards to reward staff who go above and beyond in their role.
A commitment to your development access to learning and mentoring schemes; integrated with our Academic Career Pathways.
A range of generous family-friendly policies
paid time off for parenting and caring emergencies
support for those going through the menopause
paid time off and support for fertility treatment
and more
More details can be found on our benefits page: (opens in a new window).
We are a Disability Confident Employer. If you have a disability and meet the essential criteria for this job you will be invited to take part in the next stage of the selection process.
We are a research university with a global reputation for excellence. Our ideas and expertise change the world for the better, making a real difference to society. We know that when people come together with different views, approaches and insights it can lead to richer, more creative and innovative teaching and research and the highest levels of student experience. Our University Vision ) outlines our commitment to building a diverse community of staff and students that recognises and values the abilities, backgrounds, beliefs and ways of living for everyone.