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Head of clinical operations

Stratford-upon-avon
Cancer Research UK (CRUK)
€70,000 a year
Posted: 20h ago
Offer description

Salary

Grade M3 - competitive salary


Reports to

Director of the Centre for Drug Development


Department

Research & Innovation


Contract

Permanent


Hours

Full time 35 hours per week (other flexible‑working requests will also be considered if it meets business needs)


Location

Stratford, London with high flexibility (we would expect you to be in the office 1-2 days per week). This position requires some UK and European travel to clinical sites and relevant conferences.


Closing date

Sunday 3rd May 2026 at 23.59


Visa sponsorship

Cancer Research UK can consider visa sponsorship for this vacancy. If this applies to you, please ensure that this is clearly marked on your application.


Responsibilities

* Lead and manage the Clinical Operations function, including Clinical Study Managers, Clinical Research Associates, Site Start‑Up Specialists and Clinical Study Coordinators, to deliver CDD objectives.
* Partner with functional leaders to ensure clinical trials are delivered on time, within budget, and with appropriate resourcing and efficient processes.
* Hold accountability for clinical project delivery to agreed timelines, including patient recruitment targets.
* Build, develop and motivate a high‑performing Clinical Operations team, strengthening performance management and capability.
* Ensure full compliance of all clinical activities with ICH GCP, UK and EU clinical trial regulations, and relevant EMA guidelines.
* Maintain sponsor oversight for international CDD trials, including European site management and monitoring conducted by service providers.
* Enable teams to operate effectively both within functional structures and as part of cross‑functional matrix project teams.
* Drive continuous improvement of Clinical Operations processes and procedures to optimise development speed, quality and regulatory compliance.
* Act as a key CDD contact for CRUK Technology and serve as system owner for validated clinical systems (e.g. Veeva eTMF, Stitch Trialmap, Adobe Sign), ensuring ongoing validated state.
* Build close working relationships with investigators and site staff across the Experimental Cancer Medicine Centre (ECMC) network, and act as a point of escalation with sites as required.
* Contribute as a member of the CDD leadership team, supporting strategic planning, budget management, external representation and deputising for the Director of Drug Development as required.


Qualifications


Essential

* Extensive experience of working in a drug development, clinical trial environment preferably in the pharmaceutical industry.
* Science graduate, PhD / MD or substantial relevant experience gained in a drug development capacity.
* Extensive experience of drug development within the Pharma/Biotech/CRO industry.
* Extensive clinical operations management experience, involving the design and delivery of complex processes to GCP standards.
* Extensive team management experience (including working within matrix team systems).
* Working knowledge of current legal and regulatory requirements for early clinical trials in the UK and EU, as well as regulations and guidelines for computerised systems.
* Working knowledge of UK and EU GDPR and data privacy legislation.


Desirable

* Oncology experience.
* Experience of early phase trials.
* Experience of financial management.


Benefits

We create a working environment that supports your wellbeing and provide a generous benefits package, a wide range of career and personal development opportunities and high‑quality tools. Our policies and processes enable you to improve your work‑life balance, take positive steps in your career and achieve your personal wellbeing goals.


EEO Statement

We actively encourage applications from people of all backgrounds and cultures, in particular those from ethnic minority backgrounds who are currently under‑represented. Cancer Research UK is an equal opportunity employer.


Contact

Please contact recruitment@cancer.org.uk or 020 3469 8400 as soon as possible if you require adjustments to facilitate the application or interview process.

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