About the Team GENCODE is a Global Core Biodata Resource and part of Ensembl, a world-leading provider of genomics data resources and bioinformatics software. Since 2003, GENCODE has delivered foundational reference genome annotation for the human and mouse genomes, supporting users worldwide — from major international consortia to individual researchers and clinicians. The HAVANA team forms the manual gene annotation arm of the GENCODE project, combining expert biological insight with cutting-edge computational methods to deliver reference-quality gene annotation used across research and clinical genomics. We are now seeking a GENCODE Data Analyst Project Lead to guide this work into its next phase! Could this be you? As the GENCODE Project Lead, you will lead a team of expert genomic data analysts and work closely with bioinformatics developers to integrate the latest biological knowledge, datasets, and technologies into high-quality gene annotation. Your hands-on scientific expertise will directly inform the development of manually supervised automated annotation pipelines that underpin GENCODE’s global impact. This is a senior scientific role combining leadership, deep biological insight, and computational fluency, with the opportunity to influence genome annotation across reference genomes and pangenomes. In this role you will: Lead, manage, and mentor a team of genomic data analysts, ensuring gene annotation meets the exceptionally high standards of the GENCODE project Produce and oversee manual gene and transcript annotation, contributing directly to reference-quality datasets Identify opportunities to advance gene annotation using new biological insights, technologies, and emerging data types Design and deliver projects that integrate novel datasets into annotation workflows, working closely with bioinformatics developers Improve existing annotation pipelines and tools by identifying gaps, liaising with stakeholders, and driving solutions Collaborate across Ensembl to ensure effective presentation and dissemination of gene annotation Represent the group internally and externally, including at international conferences and with external collaborators Contribute to data analysis for publications, support experimental design, and influence downstream research Write reports, documentation, and peer-reviewed publications You have (Requirements) PhD in genome science, molecular biology, genetics, or a related discipline Deep expertise in one or more of: Genome annotation Genome biology Molecular biology Comparative genomics Experience leading projects, teams, or large-scale collaborations Confident use of genome browsers (Ensembl, UCSC, NCBI) Linux/Unix command line experience Scripting and data analysis skills Familiarity with bioinformatics tools and resources Experience working with genomic and/or omics datasets Transcriptomic sequencing and alignment methods Experimental omics data generation Computational analysis of omics data Comparative genomics and evolutionary constraint Behaviours we look for in our team You are a highly motivated scientist with strong curiosity, initiative, and leadership capability. You are equally comfortable engaging with research literature, analysing genomic data, and guiding teams and collaborations. You will posses strong communication skills, with the ability to explain complex biological and computational concepts clearly A self-starter able to manage multiple priorities and deadlines, Collaborative and effective in multidisciplinary, international teams! You might also have (Desirable) Direct experience annotating gene structure and function from omics data Expertise integrating diverse datasets to improve gene annotation Experience in collaborative omics research projects A publication and presentation track record Familiarity with large-scale genome or pangenome initiatives Knowledge of non-canonical translation (e.g. Ribo-seq, immunopeptidomics) Understanding of non-coding RNA biology and associated analysis methods Other helpful information To apply: Please submit an application with a personalised cover letter and CV. Incomplete applications will not be considered Hybrid Working: At EMBL-EBI we are pleased to offer hybrid working options for all our employees. A dedicated desk will be available everyday, our team work three days on site and two from home. Interviews : We plan to hold introductory meetings with selected candidates remotely. Contract length : 3 years (grant based) Salary : Grade 7 monthly salary starting at £4,206 per month after tax but excluding pension and insurance contributions. Plus other generous benefits. Why join us Do something meaningful At EMBL-EBI you can apply your talent and passion to accelerate science and tackle some of humankind's greatest challenges. EMBL-EBI, part of the European Molecular Biology Laboratory, is a worldwide leader in the storage, analysis and dissemination of large biological datasets. We provide the global research community with access to publicly available databases and tools which are crucial for the advancement of healthcare, food security, and biodiversity. Join a culture of innovation We are located on the Wellcome Genome Campus, alongside other prominent research and biotech organisations, and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued, supported and empowered to reach their professional potential. Watch this video to see how EMBL-EBI makes an impact. Enjoy lots of benefits: Financial incentives: Monthly family, child and non-resident allowances, annual salary review, pension scheme, death benefit, long-term care, accident-at-work and unemployment insurances Flexible working arrangements - including hybrid working patterns Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover) Generous time off: 30 days annual leave per year, in addition public holidays Relocation package including installation grant (if required) Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely) Family benefits: On-site nursery, 10 days of child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances Benefits for non-UK residents: Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non-resident allowance. For detailed information please visit our employee benefits page here. What else you need to know International applicants: We recruit internationally and successful candidates are offered visa exemptions. Please take a look at our International Applicants page for further information. EMBL is a signatory of DORA. Find out how we apply DORA principles to our recruitment and performance assessment processes here. Diversity & Inclusion: At EMBL-EBI, we believe that diverse teams drive innovation and scientific excellence. We encourage applications from candidates of all genders, identities, nationalities, and/or any other diverse backgrounds. How to apply: To apply please submit a cover letter and a CV through our online system. Applications will close at 23:59 CET on the date shown below. We aim to provide a response within two weeks after the closing date. Closing Date 10/01/2026