:
1. Perform screening assessment of various bio-enhanced formulation options using a variety of techniques including spray drying (SD), small scale hot melt extrusion (HME), lipid based formulations (LBFs) and size reduction via micronisation and cryo-milling.
2. Perform physical characterisation using techniques such as differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), microscopy (Optical and Hot Stage), xray powder diffraction (XRPD), scanning electron microscopy (SEM), Raman spectroscopy, particle size analysis, rhelogy and viscometry.
3. Perform in vitro performance analysis using HPLC, Mass Spectrometry, UV-Spectroscopy, dissolution, artificial membrane permeability
4. Complete the write-up of experimental results on electronic notebook system, provide technical reports for all work conducted and present findings/recommendations to project leads/supervisors
5. Participate in Lab meetings - raising safety and quality concerns and participate in management/housekeeping audit activities
Education / Experience required:
6. degree in Analytical Science, Chemistry, Pharmacy, or equivalent industry experience, with minimum 1-3 years’ experience in a laboratory-based role, primarily in pharmaceutical industry.
7. Experience of working to industry expectations for data integrity within a non GxP environment.
8. Knowledge and experience of bio-enhancement techniques to improve drug solubility
9. Knowledge and experience of in vitro characterisation methods such as solubility and dissolution
10. Some knowledge and experience of solid state analytical methodologies such as X-Ray powder diffraction and Raman spectroscopy.
Our 4i Values:
Integrity – Innovation – Intensity – Involvement
If you resonate with our 4i values above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world’s most urgent health needs, submit your application – we’d love to hear from you