Responsibilities
* Following a variety of laboratory protocols and procedures, including but not limited to sample handling and management, tissue dissociation to single cells or nuclei, RNA/DNA extraction, preparation of libraries for RNA sequencing, embedding, cryosectioning, laser capture, microdissection and testing new protocols.
* Overseeing and managing day-to-day running of the laboratory experiments.
* Labelling and dilution of samples along with completion of manifests to support the transfer of samples internally between departments.
* Helping review and optimise SOPs and associated risk assessments to ensure maximum efficacy and efficiency with all sample types.
* Monitoring laboratory resources, re‑ordering where necessary to ensure stock levels are maintained to keep the laboratory running efficiently.
* Ensuring standards of health and safety are maintained.
* Facilitating transfer of samples, consumables, reagents and equipment.
Qualifications
* Degree in Biological Sciences, or equivalent qualification or experience.
* Relevant, post‑graduate laboratory experience.
* Significant experience of core molecular biology techniques, including PCR, RNA/DNA extraction, library preparation for Chromium 10x and similar methods.
* Experience dissecting, embedding and cryosectioning tissues.
* Ability to learn new protocols and then run them independently.
* Ability to test and implement new approaches and techniques.
* Proven process improvement/troubleshooting ability.
* Computer literate.
* Excellent laboratory practice.
* Good written and oral communication skills.
* Excellent organisational skills.
* Ability to keep good up‑to‑date records with attention to detail.
* Ability to work to a schedule and successfully manage and prioritise multiple competing projects.
* Proven experience of working within a team.
* Experience of working on collaborative projects.
About Us
The Cellular Genomics Wet Lab Support Team assists in data generation by supporting with all aspects required for delivery of the Programme science; from tissue acquisition logistics (including governance checks), sample and laboratory management, to the development, validation and implementation of novel bespoke techniques for cellular level sample interrogation.
You will have experience working in a laboratory and ability to adapt to changing priorities and protocols whilst ensuring the workflow continues at a high quality level. In this role, you will have the opportunity to conduct more bespoke experimental work utilising experience and deeper scientific understanding. There may be occasional out of hours work associated with this role.
Hybrid Working at Wellcome Sanger
We recognise that there are many benefits to Hybrid Working; including an improved work‑life balance, with more focused time, as well as the ability to organise working time so that collaborative opportunities and team discussions are facilitated on campus. The hybrid working arrangement will vary for different roles and teams. The nature of your role and the type of work you do will determine if a hybrid working arrangement is possible.
Equality, Diversity and Inclusion
We aim to attract, recruit, retain and develop talent from the widest possible talent pool, thereby gaining insight and access to different markets to generate a greater impact on the world. We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.
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