Overview
This post was established by Leeds Teaching Hospitals Trust in conjunction with Tommy's and The University of Leeds, to encourage more senior trainees to become involved in research activity and to develop specialist interest. Applications are invited for a Clinical Research Fellow (Trust doctor) in Obstetrics at ST6+ level. The specific research area relates to the microarchitecture of the cervix and its role in preterm birth. Previous research experience is desirable but not essential.
The proposed research incorporates the span of bench, clinical, and data-led studies which should appeal to a wide range of trainees with pre-existing abilities and interests. We are seeking highly motivated, enthusiastic individuals with the potential to excel in both their clinical and research training and who have the ambition to obtain a higher degree. The post is for up to 3 years with 60% of the working week dedicated to research and 40% to clinical service. There is an on-call commitment as 2nd on call for obstetrics and gynaecology on a 1 in 10 basis.
Role and Employment Details
The post holder is employed by Leeds Teaching Hospital Trust (LTHT) with an honorary contract with the University of Leeds. Applications are invited for a Clinical Research Fellow (Trust doctor) in Obstetrics ST6+ level. The specific research area relates to the microarchitecture of the cervix and its role in preterm birth. Previous research experience is desirable but not essential.
Department Information
The research work will be carried out in the Section of Obstetrics & Gynaecology within the School of Medicine, University of Leeds. The Sections work covers a range of themes ranging from understanding disease aetiology through to the application of our findings in translational clinical trials and currently includes the following areas of research:
* Prediction/prevention of adverse pregnancy outcome – aims to integrate complementary research themes to identify pre-symptomatic markers using clinical, metabolomic, proteomic, and genetic biomarkers in obstetric complications
* Gynaecological cancer – pathophysiology of endometrial cancer using genomic, transcriptomic, proteomic and lipidomic approaches; focus on the tumour microenvironment in carcinogenesis; microRNAs, predictive markers for response to therapies, epithelial-mesenchymal transition in ovarian cancer
* Interaction between nutrition and pregnancy outcome – collaboration with the Nutritional Epidemiology group to understand nutrition’s impact on pregnancy complications; research on maternal caffeine and antioxidant intake
* Endothelial biology – mechanosensing channels in placental vasculature within the cardiovascular research group
* Reproductive Medicine – pioneering in vitro maturation research and studying implantation biology
Our work is collaborative and links with other leading national and international groups. We particularly value the practical contribution of our research in driving teaching and clinical practice to improve women’s healthcare.
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