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Research associate in mapping of antibiotic uptake (10395)

East Hagbourne
Rosalind Franklin Institute
Research associate
€40,000 a year
Posted: 9h ago
Offer description

Overview

We are currently looking for a Research Associate to support Dr Pedrazo-Tardajos's Nanoscale Electron Spectroscopic Mapping of Antibiotic Uptake and Resistance Mechanisms project. Role emphasizes electron microscopy theory, methods, and technology development. The successful applicant will work on methods to visualise antibiotic uptake probed using electron spectroscopy, with the aim to visualise and quantify uptake of antibiotics in different biological targets under both liquid and cryo-EM conditions, using multidimensional electron spectroscopy. This role forms part of a wider research effort to reduce antimicrobial resistance across scales. You will contribute to the development and optimisation of novel TEM- and SEM-based microscopy and spectroscopy workflows, including EELS, under a range of conditions and across multiple dimensions in diverse environments, including liquid and cryo. You will also support data acquisition and analysis using the first chromatic aberration corrected microscope in the UK.

As a Research Associate at the Franklin, you will bring the scientific knowledge and skills needed to deliver a specific research project within a team delivering a research program. Through this work, you will build scientific independence, develop new science and leadership skills, and establish a growing external reputation. A team of scientists will support this work, enabling opportunities for future funding applications and career development.


Qualifications and Eligibility

Applications are encouraged from candidates with experimental backgrounds in physics, material science, biophysics, structural biology or related disciplines with an interest and experience of advanced EM methods. You will have access to state-of-the-art instrumentation, including: a double aberration-corrected 300kV Cryo (S)TEM, two 300kV conventional Cryo TEMs, three Cryo Dual beam FIBs and a 300kV chromatically corrected TEM for fast in situ observations alongside advanced sample preparation and computational facilities. Whilst the role requires candidates to hold a PhD/DPhil (or equivalent), we may consider candidates who have submitted their PhD/DPhil thesis, in which case the initial appointment will be made at £37,500 per annum (to be increased on completion of the PhD/DPhil qualification).


What You Will Do

You will contribute to the development and optimisation of TEM- and SEM-based microscopy and spectroscopy workflows, including EELS, under a range of conditions and across multiple dimensions in diverse environments, including liquid and cryo. You will also support data acquisition and analysis using the first chromatic aberration corrected microscope in the UK.


Application Details

Before submitting your application please ensure you read the Job Information Pack for full details of this role on our website.


Benefits

* 25 days holidays plus bank holidays and Christmas holiday shutdown
* Generous pension scheme (employer's contribution currently up to 18%)
* Group Life Assurance (also known as Group Life Insurance or Death in Service)
* Buying and Selling Annual Leave
* Workplace Nursery Salary Sacrifice Scheme
* Hub building with state-of-the-art laboratories
* Hybrid and flexible working
* Training and development opportunities for staff at all levels
* Bus pass discount scheme and good transport links to Oxford and surrounding areas
* Cycle to Work Scheme
* Access to employee discount platform (Perkbox)
* Occupational Health and wellbeing support including Employee Assistance (24/7 support and counselling)
* Health Cash Plan
* Subsidised canteen and food outlets on campus
* Free on-site parking
* Campus location in beautiful countryside with social and sports clubs open to staff
* The Franklin's underlying aim is to produce the best science for research today, and this means resolutely embracing a diverse team, who have a wide range of experiences, skills and knowledge to push forward on the innovative work our institution delivers. Both our work and our institution are better for it. For further information, view our Equality, Diversity and Inclusion Policy.
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