Site Name: UK – London – New Oxford Street
Posted Date: Oct 13 2025
SERM Scientific Director – Summary
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more: Our approach to R&D
Responsibilities
Responsibilities within the SERM (Safety Evaluation & Risk Management) group: lead medical and scientific staff, define and drive the strategy and vision of clinical safety and pharmacovigilance activities in alignment with Global Safety business strategies. As a senior member of the Global Safety organization, responsible to:
* Implement policy, processes and support the implementation of operational and strategic plans
* Ensure scientifically sound review and interpretation of data and management of safety issues; escalate safety issues identified through the safety review process to senior management and safety governance as appropriate; make recommendations for characterization, management, and communication of safety risks
* Focus on efficiency and effectiveness to meet the needs of patients and healthcare professionals; support pharmacovigilance and benefit-risk management of the assigned portfolio of GSK global assets to ensure patient safety globally
Key Responsibilities
Scientific/Medical Knowledge PV Expertise
* Expert in clinical safety and pharmacovigilance activities
* Sound judgement and decision making in safety evidence generation, benefit-risk assessment, causality assessment, evaluation of safety signals, and risk management strategies including labelling changes and education
* Coach and mentor SERM colleagues in signal evaluation methodology and regulatory safety reports
* Demonstrated ability to make quality decisions in critical situations, considering all relevant information
* Strong medical/scientific judgment, analytical skills, proactive approach in drug safety and urgency
* Champion safety governance by developing safety strategy and execution for products in development and post-marketing; address safety issues and implement risk-reduction strategies
* Lead cross-GSK activities such as safety advisory panels and governance committees
* Engage with the broader GSK and pharmacovigilance environments with professionalism
Cross-functional Matrix Team Leadership
* Ability to affect department or product strategies with global considerations
* Build collaborative relationships and demonstrate leadership in safety issues within a matrix team
* Demonstrates resilience and adaptability; leads due diligence activities
Communications and Influencing
* Excellent verbal and written communication and influencing skills
* Leads cross-GSK safety activities and interfaces with governance committees; may engage in external pharmacovigilance initiatives
* Drives change to implementation; recognized as an authority on pharmacovigilance regulations and methodologies relevant to SERM
Why you?
Basic Qualifications
* Health Sciences/Health Care Professional degree (e.g., BSc, MSc, PhD, RN/BSN/MSN, NP, RPh/B Pharm/Pharm D) for Senior Scientific Director
* Comprehensive experience in the Pharmaceutical or Biotech industry in Pharmacovigilance or Drug Safety
* Significant pharmacovigilance experience in Safety Evaluation and Risk Management across clinical development and post-marketing activities
* Knowledge of international pharmacovigilance requirements (ICH, GVP modules, CIOMS) and drug development/approval processes
* Experience working in large matrix organizations
* Prior experience in HIV therapy area desirable but not essential
Why GSK?
GSK is a global biopharma company focused on uniting science, technology and talent to get ahead of disease together. We aim to positively impact health worldwide and focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases. We are committed to an agile working culture and to creating an environment where our people can thrive. GSK is an Equal Opportunity Employer.
We encourage flexible arrangements and are happy to discuss adjustments to support your application. For adjustments, contact UKRecruitment.Adjustments@gsk.com or 0808 234 4391. Helpline hours: 8.30am–12.00 noon, Mon–Fri (times may vary on bank holidays). For other questions, see the UK Recruitment FAQ guide.
Note: This listing includes standard notices related to employment businesses/agencies and U.S. transparency reporting requirements as applicable.
Seniority level
* Not Applicable
Employment type
* Full-time
Job function
* Research, Analyst, and Information Technology
* Industries: Pharmaceutical Manufacturing
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