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Job Description
We are seeking a Post-doctoral research associate to investigate the mechanisms of mutagenesis in the human genome.
Job Description
We are seeking a Post-doctoral research associate to investigate the mechanisms of mutagenesis in the human genome.
The Opportunity
To lead a programme of original, high-quality research focusing on the molecular mechanistic details of mutagenesis in the human genome, based in the research team of Professor Martin Taylor at the Institute of Genetics and Cancer. This will be primarily through computational analysis of genomic and related data and will depend on good mechanistic understanding of cellular processes involved in genome replication, damage tolerance and repair. Analyses will entail the development of novel software tools and pipelines for new and cutting-edge analysis. There is scope to design new laboratory experiments and commission high-throughput data generation, so although primarily computational, a good understanding of practical molecular biology will be important. It is expected that the holder of this post will take a leading role in producing analyses for publication and dissemination, including contributions to manuscript writing and presenting at conferences.
This post is fixed-term until 31 st March 2028 and full-time (35 hours per week); however, we are open to considering flexible working patterns. We are also open to considering requests for hybrid working (on a non-contractual basis) that combines a mix of remote and regular on-campus working.
The salary for this post is at Grade UE07: £40,497 to £48,149 per annum, pro-rata if part-time.
Your Skills And Attributes For Success
* An inquisitive mindset.
* Demonstrated understanding of fundamental cellular processes in molecular detail, e.g. DNA replication and repair.
* Evidence of aptitude for innovative computational analysis.
* Ability to design well controlled, appropriately powered experiments or analyses.
Click here to view a copy of the full job description (opens new browser tab).
Application Information
Please ensure you include the following documents in your application:
* CV.
* Cover letter highlighting your own research interests and your most important 1 or 2 publications.
* Details of two referees.
As a valued member of our team you can expect:
* A competitive salary.
* An exciting, positive, creative, challenging and rewarding place to work.
* To be part of a diverse and vibrant international community.
* Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our staff benefits page (opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.
Championing equality, diversity and inclusion
The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.
Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our right to work webpages (opens new browser tab).
The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa. Please note if the role is offered on a part-time basis, it may result in sponsorship being dependent on a number of factors specific to the successful applicant or the role no longer meeting the Home Office’s criteria for sponsorship.
Key dates to note
The closing date for applications is 17 th July 2025.
Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.
Interviews will be held last week of July or 1 st week of August 2025.
About Us
As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.
About The Team
A deep understanding of human genome function - particularly for the non-coding genome - is an outstanding grand challenge. Our mission is to discover how our genome controls the function of molecules, cells and tissues, in health and disease, connecting human genetic variation to phenotype.
Multidisciplinary HGU research programs embrace genetic, computational, biochemical, cellular, model organism and clinical approaches, to gain meaningful insights across scales and dynamic processes, with cross-cutting themes in 4D Cellular Medicine and Genome Interpretation.
To find out more visit https://www.ed.ac.uk/mrc-human-genetics-unit
The MRC Human Genetics Unit is part of the Institute of Genetics and Cancer (IGC). This partnership with CRUK Edinburgh Centre and Centre for Genomic and Experimental Medicine Centre aims to understand development and disease by using the latest developments in genetic, genomic, cellular and clinical science. The partnership provides access to state of the art scientific facilities, scientific infrastructure and business support, including on site Advanced Imaging Resource, Animal Model support, Bioinformatics Analysis Core, DNA sequencing, Flow Cytometry, Mass Spectrometry, HTPU microarray. The IGC also offers a highly collegial environment with excellent local career development support, active social, wellbeing and sustainability related groups making it a very desirable and supportive working environment.
To find out more visit https://www.igc.ac.uk
Seniority level
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Full-time
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Research, Analyst, and Information Technology
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