Research Associate: Theories of Embryo Development (Fixed Term)
The Simons group at the Gurdon Institute is seeking a Research Associate to study the developmental dynamics of the early mammalian embryo using theoretical, statistical and computational approaches.
Alongside wet‑lab work with transgenic mouse models and 3D organ culture systems, the Simons lab performs analytical and computational studies of cell‑fate mechanisms in developing and adult tissues, focusing primarily on skin and gastrointestinal tract biology. The group prioritises defining transcriptional and epigenetic factors that mediate cell‑state transitions and cellular plasticity during development, homeostasis and regeneration.
We look for candidates with experience in developing and applying theoretical, statistical and computational methods in biology, who will use quantitative lineage‑tracing and single‑cell multi‑omics data to investigate cell‑fate mechanisms, multilineage priming and lineage segregation in mouse and human embryos, and how these programs reactivate after injury or via oncogenic mutations.
Requirements: PhD (or expected to obtain within 6 months) in a relevant subject, solid grounding in statistical and mathematical approaches to biological systems, experience with single‑cell genomics data manipulation and analysis, sound understanding of basic molecular biology, and a solid publication record. Candidates must be able to work independently and collaborate effectively in a dynamic, multidisciplinary environment.
The Simons lab is co‑located in the Gurdon Institute, the Department of Physics, Applied Mathematics and Theoretical Physics. It offers a stimulating environment that promotes collaborative and interdisciplinary research, career development and teaching opportunities, an attractive pension scheme, generous holiday allowance and employee benefits including a shopping discounts scheme.
Fixed‑term: Funding is available for 2 years initially. Please quote reference PR47814 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University ensures that all employees are eligible to live and work in the UK.
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