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Dmpk expert

Sheffield
Barrington James
Posted: 16 April
Offer description

We’re supporting a growing biotech with a strong early-stage pipeline, looking to bring in an experienced DMPK Consultant to provide senior-level input across key programmes.

This is a high-impact role focused on de-risking assets, guiding decision-making, and ensuring DMPK strategy is aligned with programme progression toward IND and beyond.


The Role

You’ll act as a strategic partner to internal teams, bringing clarity to PK, ADME, and dose-related decisions at critical inflection points.

* Provide end-to-end DMPK strategy across discovery and preclinical programmes
* Guide PK/PD modelling and dose prediction to support candidate selection
* Interpret ADME and PK datasets, translating findings into actionable insights
* Advise on and oversee outsourced studies (CROs)
* Identify and mitigate development risks ahead of IND
* Support cross-functional teams in linking preclinical data to clinical strategy


What They’re Looking For

* Extensive experience in DMPK within biotech/pharma
* Strong track record supporting programmes through preclinical → IND
* Deep understanding of PK/PD, ADME, and translational strategy
* Comfortable operating in a consultative, advisory capacity
* Ability to quickly embed and influence senior stakeholders

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