Associate Director, CMC Drug Substance
Recursion
Overview
Recursion is on the cutting edge of drug discovery, generating proprietary maps of biology that provide unique insights, driving target identification, validation, and ultimately novel clinical candidates. The Associate Director, CMC Drug Substance will advance our current and future clinical assets through development to patients in need.
In This Role, You Will
* Lead external drug substance development across our portfolio, overseeing CDMOs and strategic technical development relationships.
* Provide technical leadership, project management and oversight of drug substance process development and manufacturing activities supporting Recursion’s clinical programs.
* Ensure delivery of drug substance from external manufacturing campaigns adhering to current quality guidelines and delivery timelines. Typical travel to external manufacturing sites is 10‑20% of the time.
* Critically analyze process and analytical data to identify and resolve key synthetic challenges during drug substance development.
* Participate in developing and extending CDMO relationships, budget planning and forecasting for drug substance expenditures and achieving quality requirements.
Experience You’ll Need
* Ph.D. in organic chemistry or closely related field with a minimum of 5‑8 years of experience, or M.S. with 8‑12 years of experience.
* Strong knowledge and experience in small molecule drug substance process development and manufacturing best practices across all phases of drug development, from initial regulatory filings through registration, validation and launch.
* Prior experience leading external development and CDMO relationships is a plus.
* Demonstration of cross‑functional understanding related to drug substance development including salt/polymorph screening, phase‑appropriate analytical development, standard process of drug product development, quality and regulatory affairs.
* Well‑versed in the latest trends impacting drug substance technology, manufacturing and the outsourcing industry.
Working Location & Compensation
This is an office‑based, hybrid position at one of our offices in either Milton Park or London, England. Employees are expected to work in the office at least 50% of the time.
Estimated current annual base range: £84,000 to £98,900 (GBP). You will also be eligible for an annual bonus, equity compensation and a comprehensive benefits package.
Values We Hope You Share
* We act boldly with integrity.
* We care deeply and engage directly.
* We learn actively and adapt rapidly.
* We move with urgency because patients are waiting.
* We take ownership and accountability.
* We are One Recursion.
About Recursion
Recursion (NASDAQ: RXRX) is a clinical‑stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world’s largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine‑learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale—up to millions of wet‑lab experiments weekly—and massive computational scale—owning and operating one of the most powerful supercomputers in the world—Recursion is uniting technology, biology and chemistry to advance the future of medicine.
Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life‑sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at www.Recursion.com.
Equal Opportunity Employer
Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation.
Accommodations are available on request for candidates taking part in all aspects of the selection process.
Recruitment & Staffing Agencies
Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
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