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Background
Sygnature Discovery is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global pharma, biotech and NFP organisations.
Since 2004, Sygnature Discovery has delivered over 40 novel pre-clinical and 22 clinical compounds, with its scientists named on over 170 patents. Therapeutic areas of expertise include oncology, inflammation and immunology, neuroscience, metabolic diseases, infectious diseases, fibrotic diseases and more. To find out more, please visit www.sygnaturediscovery.com.
Director of In Vivo Pharmacology
A fantastic opportunity has become available to join our Nottingham-based In Vivo Pharmacology department as Director of In Vivo Pharmacology. This is a full-time, on-site position.
Reporting to the VP of Global In Vivo Pharmacology, the Director will play a critical leadership role in shaping the strategic direction, scientific excellence, and operational performance of Sygnature’s In Vivo Pharmacology division. This UK-based role oversees a team of 30+ in vivo scientists based in Nottingham and is responsible for delivering high-quality scientific outcomes and driving team performance.
The Director will provide inspirational leadership, foster a collaborative and innovative working environment, and work closely with the senior leadership team to identify strategic scientific focus areas and commercial growth opportunities. This role requires a strong combination of scientific expertise, leadership skills, commercial insight, and an in-depth understanding of the role in vivo pharmacology plays in integrated drug discovery.
Extensive experience in in vivo pharmacology research alongside a proven track record of leading successful project delivery within a pharma or CRO environment is essential.
Main duties and responsibilities:
* Collaborate with senior in vivo pharmacology leaders as part of global in vivo leadership team to develop and implement the global in vivo pharmacology strategy
* Strategic oversight of recruitment, training and mentoring of employees within the department to support the development of high-performing individuals and teams.
* Set clear scientific and commercial goals and performance expectations for the department, ensuring accountability is taken at all levels.
* Establish and nurture relationships with the portfolio of existing partners, coaching and supporting internal teams as needed
* Work collaboratively with the broader Sygnature Commercial team to identify and progress new business opportunities, participating in client meetings, proposals to support the winning of new stand-alone and integrated projects
Skills and Experience:
* Ph.D. in a relevant scientific discipline (e.g. pharmacology, chemistry) or equivalent extensive and relevant industry experience.
* Extensive experience with in vivo pharmacology research), with a proven track record of successful management and delivery to a portfolio of clients and/or projects within a pharma or CRO setting
* Therapeutic area expertise in metabolic (obesity, diabetes, MASH) and/or CNS disease, with a strong understanding of DMPK and PK/PD
* Strong leadership skills with previous experience developing and leading high-performing scientific teams in a multidisciplinary, matrix environment
* Strong commercial acumen with a proven ability to understand P&L, market dynamics, competitive landscape and business drivers.
* A collaborative mindset with excellent communication skills and interpersonal skills, with the ability to work effectively across many diverse organisations externally as well as functions internally
* Strategic thinking and the ability to contribute to the overall research and development strategy of the organisation
Here at Sygnature Discovery, we take pride in offering an excellent training and benefits package. As a valued employee, you will be entitled to:
* 25 days annual leave (rising with service) plus bank holidays, and buy/sell scheme
* Private Medical Insurance
* Life Insurance
* Employee Assistance Programme and mental health first aiders
* Enhanced Family Friendly Policies
* Sygnature Group Pension Scheme
* 1 paid volunteer day per year
* A host of flexible benefits to support your wellbeing and lifestyle
Why Sygnature Discovery
At Sygnature Discovery, we embody excellence in everything we do. From pioneering research to ground-breaking discoveries, we set the standard for scientific innovation. But it's collaboration that truly defines us. Across continents and disciplines, we unite to solve complex challenges, driven by a shared passion for improving lives worldwide.
We understand the importance of creating a work environment that empowers you to thrive. That’s why we have fostered a culture of collaboration and support, providing pathways for both professional and personal development. This includes a diverse range of bespoke training and development designed to accelerate both your personal and career growth.
We are committed to fostering diversity and inclusion throughout our organisation. We encourage applications from individuals of all backgrounds, ethnicity, gender identity, sexual orientation, disability, neurodiversity, age, family or parental status, beliefs, nationalities and religions. We strive to cultivate an inclusive environment where all our colleagues feel empowered to bring their true selves to work.
If you’re interested in joining a company that places people at the heart of its business, please submit your application as soon as possible as we will be interviewing on an ongoing basis.
If you have any questions or need further information, please contact the Talent Acquisition team at careers@sygnaturediscovery.com. Please do not submit your application to this email address.
Seniority level
* Seniority level
Not Applicable
Employment type
* Employment type
Full-time
Job function
* Job function
Research, Analyst, and Information Technology
* Industries
Hospitality, Food and Beverage Services, and Retail
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