ANGLE is a world-leading liquid biopsy company commercialising a patent protected platform technology that can capture rare circulating tumour cells (CTCs) from blood, in a minimally invasive way, for downstream analysis.
ANGLE’s Parsortix system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood. Parsortix technology comprises a microfluidic device that captures CTCs from blood based on their size and compressibility. CTCs are cancer cells that have detached from the primary tumour and entered the blood circulation, and they play a critical role in initiating metastasis. Once harvested, the CTCs can be comprehensively analysed to provide a wealth of information about the patient’s tumour, advancing cancer research and potentially personalized medicine. This technology has the potential to deliver profound improvements in clinical and health economic outcomes.
ANGLE has established a CTC harvest and analysis service from our UK-based Clinical Laboratory based in Guildford for customers worldwide. In alignment with company priorities, we plan to rapidly expand our services to include molecular profiling of CTCs and ctDNA using digital PCR and NGS to add to our image-based assays.
Join our Team
This is an exciting time at ANGLE and our team in Guildford are looking for a Laboratory Technician to join our Product and Technology Development team.
At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading-edge translational research into clinical diagnostics. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.
We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.
Principal Accountabilities
* Hands-on laboratory work, performing routine instrument maintenance and regular lab techniques:
o Preparing and processing blood samples using the Parsortix instrument
o Troubleshooting Parsortix functionality
* Contribute to data collection and recording according to ANGLE quality regulations
* With supervision and support, involved in data processing, analysis and reporting
* Provide technical support to other members of the team in various programs and projects in the area of Product and Technology Development
* Responsible for quality and regulatory compliance of work undertaken (ISO13485:2016)
* Contribute to running laboratory facilities, including receiving and unpacking deliveries, and adequate storing of them, formulating buffers and maintaining laboratory consumables as required
* Support aspects of Laboratory Management in a variety of tasks both in and out of the lab as and when required by line manager
* Undertake additional ad-hoc tasks as required, such as qualification or investigation of existing product operations towards improvement
* Performing downstream analysis (immunofluorescence/ IF staining and/ or Molecular)
* Processing cell samples onto microscope slides, IF staining and imaging samples using microscopes
* DNA/ RNA extraction, digital PCR, library preparation for NGS
Qualifications, Experience, Knowledge and Attributes
* B.Sc. or equivalent in Life Sciences gained on a course that includes practical laboratory work, or equivalent combination of education and experience (e.g. ‘A’ Levels and demonstrable relevant laboratory experience)
* Experience of working to strict quality standards such as ISO9001 or preferably ISO13485 would be an advantage
* Strong team player
* Strong verbal and written communication skills
* Ability to multitask and prioritise to meet deadlines
* Ability to work both independently with minimal supervision as well as in a team environment
* Continuous learner with a keen appetite for cross-disciplinary work
* An eye for detail and commitment to high-quality data
* A flexible, can-do approach to the requirements of the job
Job Requirements
Due to the nature of the role, our requirement is for this position to be Guildford-based, office hours, five days per week.
As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package.
Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.
Furthermore, please be advised that if you submit an application to us for this position, your application and personal details will be processed in accordance with our Data Privacy Notice for Job Candidates .
Important notice to Employment Businesses/Agencies
ANGLE does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact our ANGLE recruitment team to obtain prior written authorisation before referring any candidates. In the absence of such written authorisation being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of ANGLE. ANGLE shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
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