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Scientist / senior scientist - cellular immunology

Stoke-on-Trent
Northreach
Scientist
Posted: 16 April
Offer description

Scientist / Senior Scientist – Cellular Immunology (Cell Therapy)

Oxford, UK | Biotech | Lab-Based


We’re partnered with a cutting-edge biotech developing next-generation cell therapies, focused on enhancing the precision and efficacy of engineered T-cell responses in complex disease settings.

This is a highly hands-on, lab-first role — ideal for someone who wants to be at the bench, driving experiments and contributing directly to preclinical therapeutic development.



The Opportunity

You’ll join a fast-moving R&D team working across T-cell biology, assay development, and cell therapy optimisation, playing a key role in generating high-quality data to support early-stage programmes.


This role sits at the intersection of immunology, cell engineering, and translational science.


What You’ll Be Doing

* Design and execute mammalian cell culture experiments, including primary immune cells
* Develop and optimise functional and potency assays to evaluate engineered T-cell responses
* Run and analyse:
* Flow Cytometry (immunophenotyping)
* ELISA / cytokine release assays
* Western Blot
* Perform cytotoxicity, proliferation, and activation assays to assess T-cell function
* Support preclinical development of cell therapy candidates
* Contribute to experimental design, troubleshooting, and data interpretation
* Collaborate with cross-functional teams across biology and translational research



What We’re Looking For

* MSc or PhD in Immunology, Cell Biology, Molecular Biology, or related field
* Proven industry experience within biotech or pharma
* Strong hands-on expertise in:
* Mammalian cell culture
* Assay development
* Flow Cytometry
* ELISA / Western Blot
* Experience working with T-cells (essential)
* Exposure to CAR-T, TCR-T or cell therapy platforms (highly desirable)


Experience with:

* Cytotoxicity assays
* Cytokine release assays
* Comfortable working in a lab-intensive, fast-paced environment



Highly Desirable

* Experience supporting preclinical / early-stage therapeutic development
* Background in immuno-oncology or solid tumour biology
* Exposure to high-throughput or screening-based workflows
* Prior experience in a start-up or scale-up biotech



Why This Role

* Join a well-funded, high-growth biotech
* Work on next-generation cell therapies with real clinical impact
* Be part of a lean, high-performing scientific team
* Strong scope for ownership, progression, and scientific input

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