Overview
In this role, you will develop novel acquisition methods on the hybrid MRI-linear accelerator (MR-Linac) system at The Christie, and advance image processing and analysis techniques to establish quantitative imaging biomarkers, with a focus on pancreatic cancer. The position will involve developing diffusion-weighted imaging (DWI), dynamic contrast-enhanced (DCE)-MRI, and oxygen-enhanced (OE)-MRI approaches to improve radiotherapy guidance and evaluate treatment response. You will also contribute to research funded by CRUK and NIHR for other tumour sites, supporting projects in biology-guided adaptive radiotherapy and imaging biomarker development. The role involves close collaboration with a multidisciplinary team of MR and radiotherapy physicists and clinicians at The Christie and The University of Manchester.
* Develop quantitative MR acquisition methods on MR-Linac and diagnostic MR systems with a focus on pancreatic cancer.
* Develop and employ processing and analysis techniques to derive quantitative imaging biomarkers for radiotherapy-guidance and treatment response monitoring.
* Incorporate MR imaging biomarker techniques into radiotherapy workflows and test suitability.
Responsibilities
* Management: Assist the MR Research Lead in planning, provision and development of research collaborations and study management.
* Supervise and direct the work of trainee clinical scientists, and supervise undergraduate and postgraduate students within the MR Research Group.
* Magnetic resonance imaging: Develop MR methods (acquisition, processing and analysis) for quantitative MR imaging for radiotherapy guidance and treatment response monitoring with a focus on pancreatic cancer.
* Lead in certain areas of scientific support as defined by the MR Research Lead; occasional national or international travel for conferences and meetings.
* Develop novel MR techniques in oncology imaging for radiotherapy planning and apply to clinical research studies; work safely with MR systems and phantoms.
* Collaborate with clinical colleagues and professionals locally, nationally and internationally where appropriate.
* Research: Carry out defined projects with the MR Research Lead in line with grants and programmes; develop and employ MR acquisition, processing and analysis pipelines (DWI, OE-MRI, DCE-MRI) on standard MR and MR-Linac systems.
* Develop tailored software for processing and analysis; present results in peer‑reviewed journals and scientific meetings.
* Maintain Research Governance requirements and develop collaborations nationally, internationally and with industrial partners.
* Teaching and training: Contribute to teaching commitments for radiologists, radiographers and scientists involved in MR and related courses; assist in training clinical scientists and trainee physicists.
* Professional: Undertake continuing professional development, mandatory study days, identify training needs, participate in training courses, and stay informed on MR techniques, legislation and best practice.
Requirements
* PhD in magnetic resonance imaging (or closely related field) is essential; experience in safe operation of MR systems and development of quantitative MR acquisition methods.
* Experience with programming tools (e.g., Python, MATLAB) for image processing and analysis; excellent communication and collaborative skills.
* Enthusiasm to contribute within a highly collaborative team of scientists, radiographers and oncologists.
For further information or an informal discussion, please contact Michael Dubec (MR Research Lead) by email and phone.
Application and Organisation Information
The Christie NHS Foundation Trust is a leading cancer centre based in Manchester, serving a large regional population and engaged in extensive cancer research, with a large MR imaging facility and multiple MR systems across sites.
Sponsorship Information: We are an approved sponsoring organisation. Applications will be considered from applicants requiring sponsorship alongside all other applications. Not all roles are eligible for sponsorship. Review the government website for eligible roles and requirements.
Pre-Employment Checks: Identity verification is required, and other checks per NHS Employment Check Standards. External applicants may be asked to provide HMRC employment history for the most recent three years.
We are committed to equality, diversity and inclusion. We welcome applicants from all backgrounds and promote equal opportunities. The Christie NHS Foundation Trust is committed to ethical conduct and has a zero-tolerance approach to modern slavery.
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