We seek a highly motivated postdoctoral researcher to carry out a research project to develop and test new methods to make immune-cold colorectal cancer responsive to immunotherapy.
The Opportunity:
A Cancer Research Horizons funded postdoctoral position is available in the lab of Dr Kevin Myant (https://institute-genetics-cancer.ed.ac.uk/research/research-groups-a-z/myant-group). The project aims to develop and test new methods of targeting RNA splicing with the aim of activating immune responses in immune-cold colorectal cancer. The project will use patient-derived human organoid models, long read mRNA sequencing, and immunopeptidomics to determine how cancer cells respond to RNA splicing disruption. We will utilize this data to develop novel therapeutic approaches to enhance the efficacy of immunotherapies in this disease.
The post is full-time (35 hours per week) and fixed term for 18 months with the potential for extension based on the meeting of key objectives. This position would be ideally suited to a researcher wanting to bridge academic and translation/industry-related research. For more information, please contact Dr Kevin Myant (kevin.myant@ed.ac.uk).
The salary for this post is Grade UE07 £40,247 to £47,874 per annum.
Your skills and attributes for success:
* A PhD (or near completion) in cancer biology or a related biomedical field
* Previous evidence of successful project completion, in particular first author publications
* Experience working with organoid culture systems
* Bioinformatic experience, in particular RNAseq analysis or experience of long read technologies
* Ability to communicate complex information clearly
Application Information
Please ensure you include the following documents in your application:
* CV
* Cover letter outlining your motivation for applying and future career objectives
As a valued member of our team you can expect:
* To carry out exciting, disease relevant, impactful research
* To gain experience in state-of-the-art technologies providing a strong basis for a career in academic or commercial scientific research
* A competitive salary
* An exciting, positive, creative, challenging and rewarding place to work.
* To be part of a diverse and vibrant international community
* Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our staff benefits page (opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.
Championing equality, diversity and inclusion
The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.
Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our right to work webpages (opens new browser tab).
The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa.
Key dates to note
The closing date for applications is 14 February 2025.
Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browser's local time zone.
Interviews will be held in March 2025.
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