At Crossing Hurdles, we work as a referral partner. We refer candidates to Mercor that collaborates with world’s leading AI research labs to build and train cutting-edge AI models.
Organization: Mercor
Position: PK/PD Modeling / Pharmacometrics Lead
Referral partner: Crossing Hurdles
Type: Hourly Contract
Compensation: $150–$200/hour
Location: Remote
Duration: Varies by project (1–3 months typical)
Commitment: 10–40 hours/week
Role Responsibilities:
* Evaluate PK/PD and exposure–response model outputs for plausibility and quantitative rigor.
* Identify non-plausible parameter spaces, unsafe extrapolations, and high-risk assumptions.
* Design clear model evaluation rubrics that separate credible vs. non-credible predictions.
* Define quantitative sanity checks and failure conditions (parameter limits, curve fit quality, coverage issues).
* Provide example “gold-standard” PK/PD fits and concise reasoning behind key modeling decisions.
Requirements:
* Strong years of experience in quantitative pharmacology, PK/PD modeling, or pharmacometrics.
* Strong hands-on experience with exposure–response, population PK, and parameter estimation.
* Proficiency with NONMEM, Monolix, or similar modeling tools.
* Ability to interpret model results for dose justification and decision-making.
* Skilled at identifying structural issues, poor fits, and unrealistic assumptions in models.
Application process: (Takes 20 min)
* Upload resume
* AI interview based on your resume (15 min)
* Submit form