Overview
We have a new and exciting opportunity for a Senior Postdoctoral Researcher to join the new Oxford-GSK partnership focused on biostatistics and artificial intelligence for application in medicine, with a primary focus on optimizing clinical trial design.
Thematic Areas
* Decision analysis under model misspecification
* Uncertainty quantification around LLMs
* Constrained experimental design
* Combining models and combining data / Realistic simulation of clinical trials
* Developing LLMs to utilise ODEs and ProbML as tools, Code synthesis for causality
* Generalisability, transportabilty and validation of multiomics ML across biobanks
Responsibilities
You will primarily contribute to research on optimizing clinical trials, developing data-driven methodologies for dynamic site portfolio management during trial execution. This work involves creating frameworks for adaptive decision-making, using techniques from operations research and machine learning. You will be responsible for planning and managing your own research programme within the collaboration. You will work closely with Principal Investigators and industry scientists to agree clear task objectives, organise work and delegate as appropriate, keeping accurate and comprehensive records of work undertaken. You will contribute intellectually to the development of ‘pathfinder’ projects and help shape the direction of research themes and the wider partnership for delivery of new methods. Other responsibilities will include helping with supervision of PhD students, performing analysis in close contact with clinical researchers and taking responsibility for completion of data analyses. You will communicate regularly with the relevant theme leads and wider team on all issues relating to the development and application of new methods, ensuring progress and difficulties are fully up to date.
Qualifications
It is essential that you hold a PhD/DPhil in a quantitative discipline (eg Operations Research, Management Science, Statistics, Machine Learning, Applied Mathematics, Biostatistics, AI, Engineering) and have previous research experience. You will have experience in and an ability to develop research projects, with a strong publication record in peer-reviewed journals and conferences. You will have a proven ability in providing intellectual support and technical advice on projects and in assisting others in tools relating to data processing and analysis. A forward-thinking, collaborative approach to research will be essential to meet the aims of the partnership.
Application
Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date. This position is offered full time on a fixed term contract until 30 September 2028 and is funded by GSK. Only applications received before 12 midday on 6 November 2025 will be considered. Please quote 182278 on all correspondence.
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