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Scientist- tissue profiling 12 month contract

London
Hlx Life Sciences
Scientist
Posted: 7 June
Offer description

Job Title: Scientist – Tissue Handling Employment Type: 12 month Contract Location: London, UK - 100% Lab based The Role: We are seeking a highly motivated Scientist / Recent Ph.D Graduate with a background in Molecular Biology, Cell Biology, or a related field. The ideal candidate will have experience in spatial transcriptomics and proteomics, particularly using FFPE tissue samples, and a strong background in 10X Genomics library preparation for NGS. You’ll work in a fast-paced, collaborative environment, driving the development and optimization of cutting-edge spatial omics workflows in support of translational research and clinical discovery. Key Responsibilities: Design, execute, and troubleshoot experiments using 10X Genomics Visium and related platforms for spatial transcriptomics. Process and analyze FFPE and fresh frozen tissue samples for transcriptomic and proteomic profiling. Prepare high-quality NGS libraries for Illumina sequencing, ensuring data integrity and reproducibility. Optimize protocols and workflows for challenging tissues (e.g., fibrotic, adipose, cartilage, bone ). Collaborate with bioinformaticians, pathologists, and clinical researchers to interpret spatial omics data. Maintain accurate records, contribute to publications, and present findings at internal and external meetings. Required Qualifications: Ph.D. in Molecular Biology, Cell Biology, Biotechnology, or related discipline with a focus on spatial transcriptomics or proteomics. Proven experience handling FFPE tissues for transcriptomic and protein-based methods. Expertise in 10X Genomics library preparation and workflows for NGS (e.g., Chromium, Visium). Familiarity with Illumina sequencing platforms and general NGS QC metrics. Experience working with difficult tissue types such as fibrotic, adipose, cartilage, or bone. Hands-on experience in single-cell technologies (e.g., scRNA-seq, CITE-seq) is a strong plus. Preferred Skills: Strong understanding of tissue processing, histology, and immunostaining techniques. Excellent organizational and communication skills. Ability to work both independently and within cross-functional teams. What We Offer: Competitive salary and benefits package. Access to state-of-the-art facilities and research platforms. Opportunities for professional development and international collaboration. A dynamic and inclusive working environment that supports innovation and curiosity.

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