The Role We are excited to welcome a Drug Substance Production Chemist to our Alnwick team. If you enjoy hands‑on chemistry, thrive in a collaborative manufacturing environment, and want to play a key part in delivering high‑quality GMP drug substance, this could be a fantastic next step for you. In this role, you will support GMP manufacturing and scale‑up activities across a 24‑hour Monday–Friday shift pattern. You will be involved in batch synthesis, in‑process testing, maintaining clear and accurate documentation, and working closely with colleagues in QC and across the wider site. It is a great opportunity to grow your experience within a supportive team and a fast‑paced, science‑driven environment. Key Responsibilities Carry out drug substance manufacturing and scale‑up operations in accordance with regulatory and company procedures, including shift working as required. Perform in‑process analysis, including sample preparation, interpretation of results, and usage testing of critical raw materials and intermediates. Operate within Environmental, Health and Safety guidelines and regulations. Maintain equipment usage logs, calibration records, and Laboratory Notebooks. Liaise with the QC team to ensure in‑process analyses are completed in line with the production plan. Review completed Batch Synthesis Instructions and other process documentation. Contribute to the preparation of quality documentation, including changes, unplanned deviations, and corrective actions. Support EHS risk assessments and CoSHH assessments. Participate in process risk assessments and continuous improvement activities. Contribute to raw material and equipment acquisition, maintenance, installation, and validation as required. Carry out sampling and booking‑in of materials into the Materials Management System and maintain effective stock control for manufacturing activities. Maintain a high standard of housekeeping and manage waste disposal, liaising with relevant departments as required. Ensure that manufacturing and scale‑up operations, and all associated documentation, comply with GMP, regulatory requirements, internal procedures, and client expectations. Work with due regard to the health and safety of yourself and others. Work flexibly across the site to meet business needs. Skills and Experience Required Essential A degree (or equivalent) in Chemistry or a closely related discipline, or a completed apprenticeship as a chemical operator. A strong interest in practical chemistry and manufacturing processes. Good attention to detail and a proactive approach to documentation and compliance. Willingness to work a shift pattern within a GMP environment. Desirable Experience in GMP, pharmaceutical, or chemical manufacturing. Previous experience working in a shift‑based role. Familiarity with batch manufacturing, scale‑up operations, or in‑process analytical techniques.