Higher or Senior Scientific Officer, Sutton
Client: The Institute of Cancer Research
Location: Sutton, United Kingdom
Job Category: Other
EU work permit required: Yes
Job Reference:
35e587dd2069
Job Views:
9
Posted:
29.04.2025
Expiry Date:
13.06.2025
Job Description:
Under the guidance of Prof Trevor Graham, we are seeking to recruit a Higher or Senior Scientific Officer to study epigenome evolution in colorectal cancer. The successful candidate will play a key role in researching the evolutionary dynamics that underpin colorectal cancer development and response to treatment. The postholder will lead experimental lab work to generate and analyze molecular genomics data, especially single-cell data, from patient material and other sample types.
About you
The successful candidate must have:
* PhD in molecular biology or another relevant area.
* Ability to perform advanced NGS experiments for the analysis of cancer genomes.
* Ability to conduct single cell/nuclei dissociation, sorting, and NGS analysis in cell lines and/or patient biopsies.
* Proven expertise in advanced NGS technologies, including RNA-seq, DNA-seq, and single-cell sequencing.
* Hands-on experience with single-cell technologies such as scRNA-seq, scATAC-seq, or spatial transcriptomics.
* Good communication skills and the ability to interact effectively with other team members.
Department/Directorate Information
The Centre for Evolution and Cancer (CEC), within the Division of Cancer Biology, is a multidisciplinary centre, comprising around 50 staff dedicated to understanding cancer evolution and leveraging this knowledge for translational benefit. Our interests span early detection through to treatment of metastatic disease. The CEC brings together expertise in evolutionary theory, computational biology, and bioinformatics, combined with cutting-edge research in cell and molecular biology, providing a stimulating and creative interdisciplinary environment for innovative cancer research.
The Genomics and Evolutionary Dynamics team combines molecular and cellular biology with mathematical and computational modelling to study the evolution of malignancy. Our focus areas include early detection in the gastrointestinal tract, colorectal cancer evolution and treatment response, and pan-cancer genomics. We conduct basic research into the biology of the human body in health and disease, translating findings to improve clinical care for cancer patients.
What we offer
* A dynamic and supportive research environment
* Access to state-of-the-art facilities and professional development opportunities
* Collaboration with leading researchers in the field
* Competitive salary and pension
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