Responsibilities:
* Conduct mass spectrometry analyses for comprehensive characterization of biologics and biotherapeutics, including intact, reduced, subunit, and peptide mapping approaches.
* Perform regular analytical assessments of biologics utilizing methods such as Size Exclusion Chromatography (SEC), Reverse Phase Liquid Chromatography (RPLC), Capillary Electrophoresis (CE), and automation technologies.
* Ensure the optimal functioning of laboratory equipment through routine maintenance and effective troubleshooting of experimental challenges.
* Evaluate, document, and succinctly report experimental data, formulate well-supported conclusions, and design subsequent experiments informed by multidisciplinary insights.
* Document laboratory activities in Electronic Laboratory Notebooks (ELN) in accordance with best practices for good documentation.
* Work closely with other scientists and departments to ensure alignment and progress on project goals.
* Contribute to team discussions, share valuable insights, and present experimental findings and progress updates to colleagues and stakeholders.
Requirements:
* Bachelor's or Master's degree in Chemistry/Biochemistry with over 3 years of relevant experience.
* Demonstrated hands-on expertise with various mass spectrometry platforms, including Orbitrap and Q-ToF, along with proficiency in MS workflows for protein characterization and the use of MS software for analyzing both routine and complex datasets.
* Solid analytical proficiency in a range of chromatographic and capillary electrophoresis techniques.
* Familiarity with biophysical and structural methods, such as Dynamic Light Scattering (DLS), Differential Scanning Fluorimetry (DSF), Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS), and X-ray crystallography, is a plus.
* Experience in working with biologics, monoclonal antibodies, and/or protein therapeutics is a plus.
* Goal-oriented team player with exceptional verbal and written communication skills, a strong positive attitude, and the ability to thrive in a fast-paced, multidisciplinary environment.
* Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance.
* Learns fast, grasps the "essence" and can change course quickly when indicated.
Raises the bar and is never satisfied with the status quo.
* Creates a learning environment, open to suggestions and experimentation for improvement.
* Embraces the ideas of others, nurtures innovation and manages innovation to reality.