Overview
We are seeking to appoint a Research Associate to join the Ryten Group at the UK Dementia Research Institute at the University of Cambridge. This fixed‑term post is available for 36 months.
Responsibilities
The successful candidate will investigate transcript‑specific regulatory mechanisms underlying cell‑type‑selective gene expression in neurodegenerative disease. The role will focus on defining how alternative promoter usage, transcription initiation, and transcript isoform diversity influence RNA regulation and downstream cellular phenotypes. Working within an interdisciplinary research programme integrating long‑read and single‑cell transcriptomics with translational RNA therapeutic development, the postholder will develop and apply novel computational approaches to identify regulatory features governing transcript expression in neuronal and glial systems. This work will contribute to mechanistic understanding of neurodegenerative disease biology and inform rational design of precision RNA‑targeted therapeutic strategies.
Contact
For informal inquiries regarding the role, contact Professor Mina Ryten mr2022@cam.ac.uk. The role will be based at the UK DRI, Island Research Building, Cambridge Biomedical Campus, CB2 0AH.
Qualifications
Applicants must have (or be close to obtaining) a PhD. Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38 £34,610) moving to Research Associate (Grade 7) upon confirmation of your PhD award.
Equal Opportunities
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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