We seek a post-doctoral research scientist to work on a project, funded by the Medical Research Council, to study the regulation of the NLRP3 inflammasome. NLRP3-dependent inflammation is implicated in disease and through understanding the fundamental mechanisms of its regulation we hope to identify new ways of targeting inflammation. The successful candidate will join the lab of Prof. David Brough and work closely alongside the labs of Prof. Martin Lowe and Prof. Kevin Couper based in FBMH.
The successful candidate will have (or expect to hold shortly) a PhD with a strong background in cell biology, immunology and, ideally, neuroscience. The candidate must have excellent technical skills in cell and molecular biology, microscopy, flow cytometry, and have experience of working with murine models, preferably models of inflammation. Training will be available in all areas of the project.
This full-time post is for up to 36 months, with an anticipated start date of the 1st of April 2026.
What you will get in return:
* Fantastic market leading Pension scheme
* Excellent employee health and wellbeing services including an Employee Assistance Programme
* Exceptional starting annual leave entitlement, plus bank holidays
* Additional paid closure over the Christmas period
* Local and national discounts at a range of major retailers
As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
Our University is positive about flexible working you can find out more here
Hybrid working arrangements may be considered.
Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.
Any recruitment enquiries from recruitment agencies should be directed to People.Recruitment@manchester.ac.uk .
Any CV’s submitted by a recruitment agency will be considered a gift.
Enquiries about the vacancy, shortlisting and interviews:
Name: David Brough
Email: David.brough@manchester.ac.uk
General enquiries:
Email: People.recruitment@manchester.ac.uk
Technical support:
This vacancy will close for applications at midnight on the closing date.
Please see the link below for the Further Particulars document which contains the person specification criteria.