Overview
The post-holder will be responsible for carrying out research to develop iPSC-derived lung cell models. Working within a team of biochemists, cell and structural biologists, you will perform experimental work to apply omics technologies, advanced microscopy and bioimaging methods to understand dynamic cellular aspects of ciliary dynein assembly.
Responsibilities
* Carry out research to develop iPSC-derived lung cell models.
* Perform experimental work applying omics technologies, advanced microscopy and bioimaging to study dynamic cellular aspects of ciliary dynein assembly.
Qualifications
* Hold, or be close to completion of, a PhD/DPhil in biochemistry, with relevant experience in stem cell biology.
* Extensive hands-on experience in culturing human iPSCs and iPSC-derived cellular models.
* Experience with molecular cloning and generating knockout/knockdowns in iPSC-derived systems (e.g. shRNA, lentiviral transductions and CRISPR/Cas9).
* Excellent organisational and communication skills.
Location: Sir William Dunn School of Pathology, South Parks Road, Oxford
We are seeking to appoint a talented and ambitious Postdoctoral Research Assistant to join a dynamic and productive research group of Dr Girish Ram Mali, based at the Sir William Dunn School of Pathology, University of Oxford. The overall goal of the project is to establish iPSC lines for mechanistic studies on ciliary dynein motor assembly and regulation.
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