Overview
Applications are invited to the above role to support the principal investigator Professor Paul Dyer in conducting research in fungal biology, specifically to investigate the sexual biology of the opportunistic pathogen Aspergillus fumigatus. This post is part of a collaborative multinational Wellcome Trust award involving academic and medical collaborative partners in the UK and South Africa with the aim of understanding the biology of adaptation in fungal pathogens. The post will use a combination of classical, genomic, molecular and bioinformatic techniques to investigate the sexual biology of Aspergillus fumigatus, a principal cause of aspergillosis disease in humans. Specific aims are to understand the genetic basis of differences in sexual fertility between isolates and how gene flow contributes to pathogen evolution and development of antifungal resistance. The post holder will be expected to undertake independent research as well as working as part of a team, and will be responsible for writing up their work in order to contribute to published outcomes.
The role holder will have the opportunity to use their initiative and creativity to identify areas for research, develop research methods and extend their research portfolio.
Responsibilities
* Undertake independent research as well as collaborative work within a team.
* Apply a range of approaches or methodologies appropriate to the research, including classical, genomic, molecular and bioinformatic techniques to study the sexual biology of Aspergillus fumigatus.
* Investigate the genetic basis of differences in sexual fertility between isolates and how gene flow contributes to pathogen evolution and antifungal resistance.
* Write up research findings for publication and contribute to published outcomes.
* Identify areas for research, develop methods, and extend the research portfolio using initiative and creativity.
Qualifications
* PhD (or near submission) in a relevant field of Microbiology, ideally involving Fungal Biology/Medical Mycology.
* Understanding of microbial laboratory practices and skills in microbial culture of fungi.
* Familiarity with molecular biology techniques (DNA and RNA extraction, electrophoresis, PCR and qRT-PCR) including fungal transformation, and bioinformatic skills.
* Previous experience of working with filamentous fungi and/or yeasts is essential; experience with Aspergillus species or other pathogens is highly desirable.
Details
This full-time fixed-term role is available immediately for 36 months. To apply for the post please submit a cover letter and full academic curriculum vitae.
Enquiries
Informal enquiries may be addressed to Paul Dyer at the following email address: paul.dyer@nottingham.ac.uk. Please note that applications sent directly to this E-mail address will not be accepted. For background to the work please see the following references: doi:10.3390/jof6040258, doi:10.1038/nature07528, doi.org/10.1016/j.fbr.2020.10.003, doi:10.1371/journal.pbio.3002278, nature.com/articles/s41564-022-01091-2.
Equality and Inclusion
The School of Life Sciences holds an Athena Swan Gold Award, in recognition of our commitment to supporting and advancing equality and inclusion in the Life Sciences.
Our university is a supportive, inclusive, caring and positive community. We welcome those of different cultures, ethnicities and beliefs; this diversity is vital to our success and enriches life on campus. Details are available on the Equality, Diversity and Inclusion information page.
We are a Disability Confident Employer (Level 2) and are committed to the aims of the Disability Confident Scheme. We are proud to have achieved Athena Swan Gold Award.
To help you succeed, we provide guidance on the application and interview process. Details are available on the Candidate Guidance page. Discover our benefits on the Your Benefits website. We welcome applications from UK, Europe and worldwide and aim to help with the transition to the UK. See the Moving to Nottingham page for details. Your application will be considered on an equal basis, subject to the relevant permission to work in the UK as set out by the UK Visas & Immigration.
Salary: £31,387 to £35,116 per annum, depending on skills and experience (minimum £34,866 with relevant PhD). Salary progression beyond this scale is subject to performance.
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