Join to apply for the Senior Research Associate, In Vivo role at Jnana Therapeutics.
Overview
Jnana Therapeutics is a clinical-stage biotechnology company leveraging its RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana focuses on developing first- and best-in-class oral therapies for diseases including rare diseases and immune-mediated diseases. Our lead program, JNT-517, targets an allosteric site on the phenylalanine transporter SLC6A19 and is a potential first-in-class oral therapy for PKU. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development with an experienced management team.
For more information, please visit www.jnanatx.com and follow us on LinkedIn.
At Jnana, you'll join a diverse, passionate team dedicated to advancing therapies for challenging diseases. Our collaborative, purpose-driven culture fosters innovation, urgency, and belonging—making Jnana a great place to work.
Responsibilities
* Implement acute PK/PD models to screen novel compounds for autoimmune targets.
* Ex vivo assessment of study samples using MSD, ELISA, and multi-color flow cytometric analysis.
* Perform independent data analysis and interpretation to support outlining of next steps and recommendations on research approaches.
* Clearly document and communicate research outcomes to colleagues at team- and company-level science meetings.
* Occasional weekend monitoring/dosing of studies.
Qualifications
* Bachelor’s degree in Pharmacology, Biology, or related field with 3+ years of industry experience.
* Must be highly competent in IV, PO, SC and IP dosing of mice, and in-life and terminal blood collection.
* Experience running PK/PD models.
* Experience running mouse models of autoimmunity is a plus.
* Desire to quickly gain independence; strong communication and attention to detail; scientific motivation; ability to work in a fast-paced team with high independence.
About Us
Jnana Therapeutics, a wholly owned subsidiary of Otsuka Pharmaceutical, is a clinical-stage biotechnology company leveraging its RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana focuses on developing first- and best-in-class oral therapies for diseases including rare diseases and immune-mediated diseases. Jnana’s lead program, JNT-517, targets an allosteric site on the phenylalanine transporter SLC6A19 for potential PKU therapy. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development, and a highly experienced management team. For more information, please visit www.jnanatx.com and follow us on Twitter/X and LinkedIn.
At Jnana, you'll join a diverse, passionate team dedicated to advancing therapies for challenging diseases. Our collaborative, purpose-driven culture fosters innovation, urgency, and belonging—making Jnana a great place to work.
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