Overview
Biostatistician - Cancer Research UK Clinical Trials Unit - 105965 - Grade 7
Location: University of Birmingham, Edgbaston, Birmingham UK
Full time, fixed term contract up to January 2028. Closing date: 22 September 2025. UK and international travel may be required for this role.
Position The Cancer Research UK Clinical Trials Unit (CRCTU), School of Medical Sciences, College of Medicine and Health, University of Birmingham, invites applications for a Biostatistician to be the main statistical scientist for a methodological project on improving statistical methods for the design and analysis of clinical trials in paediatric cancer, funded by UKRI Better Methods, Better Research Programme.
Background The CRCTU is a leading UK clinical trials unit with a multidisciplinary team; the post holder will work within the CRCTU Biostatistics Group, collaborating with investigators, clinicians and patient representatives, and may teach at undergraduate and postgraduate level.
Role Summary
This post is for a Biostatistician to lead a methodological project focused on using ordinal longitudinal outcomes and appropriate statistical modelling to improve statistical efficiency in paediatric cancer trials. The post holder will coordinate the project, ensure timely and on-budget delivery, liaise with investigators and other institutions, and lead presentation and publication of outputs. There are opportunities to collaborate with other CRCTU Biostatistics Group members and contribute to teaching.
Main Duties
* Be the main statistician for the project investigating statistical methods for paediatric cancer trials, collaborating with investigators and other CRCTU Biostatistics Group members.
* Complete and publish a systematic review of statistical methods in paediatric cancer trials.
* Design ordinal outcome measures for specific diseases in collaboration with clinicians and patient representatives.
* Conduct and report reanalyses of trial data sets.
* Design, perform and report simulation studies to support reanalyses of real trial data sets.
* Contribute to reports, presentations, and publications of the project outputs.
* Develop recommendations for presentation and communication of results using longitudinal ordinal outcomes.
* Organise a training workshop to disseminate methods.
* Collaborate on relevant trial-related methodology projects with CRCTU researchers and other institutions.
* Provide training for other statisticians in statistical and clinical trial methodology.
* Support the delivery of clinical research in accordance with GCP, the Declaration of Helsinki, applicable legislation and policies to protect research subjects and the quality of studies.
* Promotes equality and values diversity, and fosters an inclusive working culture.
* Supports the University’s sustainability agenda through resource-efficient working.
* Any other duties commensurate with the grade.
Required Knowledge, Skills, Qualifications, Experience
* MSc in medical statistics (or equivalent) or relevant experience; if no equivalent qualification, substantial practical experience demonstrating conceptual understanding.
* Knowledge of statistical modelling and Bayesian methods.
* Knowledge of statistical software, particularly R, and strong statistical programming skills.
* Understanding of clinical trials.
* Ability to work on own initiative and in a team; good interpersonal communication skills to explain statistical concepts to non-statisticians.
* Up-to-date specialist understanding in a relevant scientific, technical or IT field.
* Evidence of literacy and numeracy.
* Knowledge of the Equality Act 2010 protected characteristics and commitment to treating all people fairly.
Further particulars can be found here. Informal enquiries to Professor Simon Gates (S.Gates@bham.ac.uk). View our staff values and behaviours here.
We value diversity and are committed to an inclusive environment. We hold Athena SWAN, Race Equality Charter and Disability Confident accreditations and have an Equality Diversity and Inclusion Centre. We also support sustainability initiatives.
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