About Oxford BioTherapeutics
Oxford BioTherapeutics (OBT) is a clinical‑stage biotechnology company developing antibody therapeutics for the treatment of cancer. You will play an integral role in the pre‑clinical development of novel immuno‑oncology therapeutics. Our OGAP® platform is the world largest, cancer‑specific, membrane protein library, directly measuring plasma membrane protein expression in patient tumors. OGAP is used to identify novel, highly tumour‑specific antigens for novel first‑in‑class ADC, Bispecific T‑cell Engager (BITE®) and Chimeric Antigen Receptor (CAR) targets. Our lead asset, OBT076, is an Antibody Drug Conjugate (ADC) in Phase 1b clinical development. Our clinical and pre‑clinical pipeline of novel biologics is balanced between internal programmes, focused on ADCs and checkpoint regulators, and externally partnered programmes with key innovators in oncology such as Roche, Boehringer Ingelheim and Zymeworks. For further information, please check our website www.oxfordbiotherapeutics.com
Purpose of the Role
In this role, you will support the discovery, investigation, and presentation of therapeutic cancer targets using bioinformatics‑based approaches. Training will be provided as needed. This position would be ideal for a bioinformatics graduate with an interest in cancer biology and/or mass spectrometry‑based proteomics.
Essential Duties and Responsibilities
* Assist with bioinformatic pipeline including researching and annotating proteins of interest from internal and public resources.
* Assist with several routine bioinformatics tasks to support business development, target discovery and US labs.
* Work with the wider bioinformatics team to implement ad‑hoc tasks for business development, target discovery and US teams where appropriate.
* Create and develop new and existing bioinformatic tools.
* Analyse, summarise and present data.
* Assist with any other functional areas as needed.
Knowledge, Experience, and Skills
* Good knowledge of programming and an interest in developing these skills (e.g. Python, R).
* Master’s degree from a computational or biological related course (e.g. biology, bioinformatics, computer science, etc.).
* Experience reading and summarising scientific literature.
* Basic knowledge of proteomics and cancer biology beneficial but not essential.
* Good written and spoken English.
* Familiarity with Microsoft Office (Excel, PowerPoint, Word).
* Good knowledge of statistics and an interest in developing these skills.
Benefits
* Health Cash Plan.
* Generous pension scheme with potential employer contribution of up to 10% (based on match contributions).
* Discretionary Annual bonus scheme.
* Free onsite parking.
* Enhanced holiday entitlement above statutory minimum plus public holidays.
* Employee Referral Bonus Programme.
* New hire share options.
* Team building events and activities.
Equality Statement
OBT is an equal opportunity employer and prohibits unlawful discrimination based on race, colour, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status. All qualified applicants will receive consideration for employment.
Why Join Us
We promote a culture of innovation, responsibility, and commitment to our goals and objectives. Together, we believe we can pool our resources and our uniqueness to develop novel, robust cures for one of the most challenging health conditions today. We recognize that our team is only as good as the people in it. Our people have described the culture as friendly, collaborative, and hard working. This is why we strive to provide a working environment that is based on cooperation, innovation, and mutual respect.
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