Job Description
4basebio is an innovative gene synthesis company with the ambition to provide high quality, synthetic DNA for use in gene therapy and gene editing platforms. We are expanding our MSAT team at our site just north of Cambridge, UK to facilitate the purification of synthetic DNA products for use in AAV, IVT mRNA processes and other therapeutic areas. We are looking for dynamic and experienced team members to help us achieve our ambitions and goals.
The role will support the development, optimisation and validation of new products within the company.
In addition, there will be opportunity for the candidate to interact with multi-disciplinary teams within the Research department and expand their laboratory skill set.
Responsibilities:
* Work to develop and optimise new and existing DNA products
* Perform screening and optimisation experiments using 4basebio DNA
* Generate documentation, such as reports/experimental write-ups, that support the development & optimisation of production processes
* Support troubleshooting activities and assist with continuous improvement initiatives
* Work to develop and optimise processes within MSAT, to ensure successful manufacture of DNA products
* Perform analysis of experimental data
* Work collaboratively to support the R&D and manufacturing functions of the Company
* Record experimental methods and results to a high standard and in-line with company guidelines
* Present commercial data to a high standard in internal meetings
* Keep up to date with relevant scientific and technical developments
* Attend and participate in relevant meetings, training, and development sessions
* Use, maintain and respect company equipment in accordance with the company’s SOPs and health & safety guidelines
* Undertake any other appropriate roles and responsibilities that reasonably fall within the role holder’s skills and experience as requested
* Be prepared to travel to other 4basebio sites
Person Specification:
* BSc in biological sciences, or a related discipline
* Experience of experimental planning, experimental design and data analysis is required
* Extensive practical experience of techniques including gel electrophoresis, DNA & RNA handling and DNA quantification is required
* Strong knowledge and practical experience in molecular biology techniques
* Highly confident in pipetting techniques
* Excellent team working and communication skills
* Excellent record keeping skills
* Must hold right to work in the UK
What we offer:
Competitive salary + comprehensive benefits package
Location:
This role is located in Over, North of Cambridge
We are unable to offer sponsorship for this role.
Due to the high number of applicants, if you do not hear back from us within six weeks, we thank you for your interest, but please assume you have not been selected for interview on this occasion.
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