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Principal scientist i analytical development & validation - oxford

Milton (Cambridgeshire)
Permanent
Immunocore
Principal scientist
Posted: 1 September
Offer description

Principal Scientist I Analytical Development & Validation - Oxford

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
As Principal Scientist, Analytical Development, you will set and influence analytical strategies across Immunocore's therapeutic project portfolio. You will provide ICH-compliant assay validation expertise and lead the development and qualification of advanced biophysical analytical methods to support drug substance and product testing. You will act as a strategic partner within cross-functional teams and deliver high-quality analytical data and regulatory documentation that drive the success of Immunocore's therapeutic pipeline.
KEY RESPONSIBILITIES
* Set and influence analytical program strategies across our therapeutic project portfolio
* Represent analytical development within cross-functional project teams, providing strategic support and technical consultancy
* Provide ICH compliant assay validation expertise to the department
* Oversee development and qualification of biophysical analytical methods including electrophoretic and chromatographic (eg. CE-SDS, SE-HPLC, IEX-HPLC, icIEF, excipient quantitation, titre assessment) methods to support drug substance and drug product release and stability testing for the Immunocore therapeutic drug portfolio.
* Oversee technical

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