We are seeking a Research Assistant to join the Stathopoulou Research Group at the Institute of Developmental & Regenerative Medicine (IDRM), part of the Department of Paediatrics at the University of Oxford. This is an exciting opportunity to contribute to cutting-edge research into the genetic and epigenetic mechanisms underpinning cardiovascular development and congenital heart disease, within a world-leading biomedical research environment. Location: Stathopoulou Research Group, Institute of Developmental and Regenerative Medicine (IDRM), Old Road Campus, Oxford Salary: £35,681–£41,636 per annum Contract type: Full-time, fixed-term for 2 years About the Role The Stathopoulou Group, led by Dr Nancy Stathopoulou, investigates how chromatin remodellers and regulatory elements control normal heart development and how disruption of these processes leads to disease. The group combines developmental biology, stem cell biology, genomics, and in vivo models to address fundamental questions with clear translational relevance. This research is supported by the British Heart Foundation and embedded within the multidisciplinary IDRM research community As a Research Assistant, you will support a diverse portfolio of laboratory-based projects using mouse and human embryonic stem cells, in vitro differentiation systems, and advanced molecular biology techniques. You will contribute to experiments employing next-generation sequencing approaches such as RNA-seq, ATAC-seq, and CUT&RUN-seq, alongside histology, imaging, and confocal microscopy where appropriate. You will play a key role in maintaining high-quality laboratory operations, keeping accurate experimental records, supporting data collection and analysis, and contributing to scientific reports, presentations, and publications. Working closely with Dr Stathopoulou, postdoctoral researchers, and students, you will be part of a collaborative, supportive team that values initiative, problem-solving, and scientific rigour. This is a hands-on, varied role blending experimental research, data handling, and teamwork—ideal for someone looking to develop strong technical expertise and deepen their experience in developmental biology, epigenetics, and cardiovascular research. About You You will hold a BSc and/or MSc in a relevant discipline such as biological sciences, molecular biology, biochemistry, or a related field, with a solid understanding of developmental, cellular, and molecular biology principles. You will have practical experience working in a laboratory environment and be confident with core molecular biology techniques and experimental protocols. You will bring strong organisational skills, attention to detail, and a commitment to maintaining accurate research records and high laboratory standards. You will be able to work both independently and collaboratively, manage your own research activities, and adapt to changing experimental demands. Experience with stem cell culture, advanced molecular biology methods, gene editing approaches, imaging, or next-generation sequencing techniques is highly desirable, as is familiarity with mouse models or genomics data analysis. A willingness to learn new skills, troubleshoot experiments, and contribute proactively to ongoing projects will be essential for success in this role. Excellent communication skills and enthusiasm for contributing to high-quality, impactful research in cardiovascular development and disease will help you thrive within the Stathopoulou Research Group. About Us The Department of Paediatrics at the University of Oxford is a vibrant and inclusive community at the forefront of child health research and clinical care. Our academics and clinicians work side by side to translate world-leading scientific discoveries into real benefits for children and families locally, nationally, and globally. We hold the Athena Swan Gold Award, recognising our commitment to equality, inclusivity, and staff development. Alongside a welcoming culture rooted in wellbeing, we offer opportunities for personal growth, collaboration, and meaningful impact. As part of the Medical Sciences Division, you will join one of the world’s leading environments for biomedical and clinical research, with state-of-the-art facilities and a strong culture of innovation and excellence. What We Offer Working at the University of Oxford offers several exclusive benefits, such as: 38 days of annual leave (inclusive of public holidays) to support your wellbeing, with the option to purchase up to 10 extra days. One of the most generous family leave schemes in UK higher education, offering up to 26 weeks of full-pay maternity and adoption leave, plus 12 weeks of full-pay paternity/partner leave. An excellent contributory pension scheme. Affordable and sustainable commuting options, including a cycle loan scheme, discounted bus travel, and season ticket loans. Access to a vibrant community through our social, cultural, and sports clubs. The closing date for applications is 12:00pm (GMT) on 20 January 2026. You can view more details by clicking the ‘Apply’ button.