Position: Senior Medical Director Location: Cambridge, United Kingdom George Higginson is currently searching for an experienced Senior Medical Director to play a pivotal leadership role in advancing a Clinical-stage Biotech's clinical development programs through late-stage development.
Apply fast, check the full description by scrolling below to find out the full requirements for this role.
Reporting to the Chief Medical Officer, you’ll provide medical oversight across global trials, contribute to regulatory strategy, and ensure GCP compliance throughout.
This is a high-impact role for a strategic clinical leader who thrives in a fast-paced, cross-functional environment.
Main Responsibilities: Lead the medical content and strategy across late-phase development programs.
Provide clinical and scientific leadership to internal teams and external partners (e.g.
CROs, consultants).
Ensure robust medical oversight of studies and safety data, in collaboration with PV and Clinical Operations.
Act as a key contributor to regulatory submissions (NDA/BLA) and represent the company in Health Authority meetings.
Serve as deputy to the CMO when required, and a core member of the Drug Safety Committee.
Oversee medical input on protocol design, study conduct, data review, and benefit-risk assessments.
Collaborate closely with Medical Affairs and Commercial to align clinical strategy with broader goals.
Recruit, lead, and develop high-performing medical staff as needed.
Requirements: Qualified physician (GMC registered or eligible).
10 years of experience in clinical development with a strong focus on Phase 3 programs.
Proven track record of leading global trials and interfacing with regulatory agencies (FDA/EMA).
Strong knowledge of GCP, ICH guidelines, and pharmacovigilance.
Skilled at interpreting complex data and making informed, strategic decisions.
Experienced in matrix leadership and cross-functional collaboration.
'Nice-to-haves': Background in Dermatology or Rheumatology.
Experience with Biologics and/or Immunology.
Prior involvement in NDA/BLA or MAA submissions.
What We’re Looking For: A strategic thinker with a strong scientific foundation and operational awareness.
A collaborative leader and effective communicator, comfortable operating at executive level.
A hands-on contributor who can switch seamlessly between big-picture planning and day-to-day execution.
This is a fantastic opportunity to be a key part of a true-underdog clinical-stage Biotech, soon approaching a BLA submission.
Apply today to take the next step in your leadership journey!