The ICR is seeking an established research leader in cancer biology with a track record in target validation for drug discovery to be the Director of the Centre for Target Validation (CTV). The appointee will provide scientific and strategic leadership of the CTV, ensuring a pipeline of robust, clinically relevant targets for drug discovery programmes within the ICR’s Centre for Cancer Drug Discovery (CCDD). They will collaborate with scientists across the ICR to identify target validation projects with therapeutic potential that are suitable to benefit from the Centre’s dedicated resource and scientific expertise. They will lead, direct, and participate in multidisciplinary projects to define/refine therapeutic hypotheses, examine mechanisms of target modulation, and explore biomarkers and patient selection criteria. Working with the CTV Deputy Director, they will ensure that ICR expertise in drug target identification is effectively translated to drug discovery programmes at ICR and with external partners.
Key Requirements
The appointee will lead an independent research group contributing to the discovery of novel targets and/or innovative small molecule anticancer therapies, aligned with the strategy and goals of the CTV / CCDD. The role requires expertise in cancer biology and substantial experience in target identification & validation; experience of later drug discovery stages is valued. We envisage that applicants will have either significant commercial experience or have a strong academic track record in cancer biology for target validation; or will have a combination of both backgrounds.
As part of your online application you will be required to upload your full CV which will pre-populate your application form.
Department/Directorate Information: