Site Name: UK - Hertfordshire - Stevenage, GSK HQ, USA - Massachusetts - Waltham, USA - Pennsylvania - Upper Providence
Posted Date: Apr 2 2026
Overview
Business Introduction: At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, focusing efforts on accelerating assets that meet patients’ needs and have the highest probability of success. We unite science, technology, and talent to get ahead of disease together.
Position Summary
The Respiratory, Immunology and Inflammation Translational Unit (RIITU), within RIIRU therapy area, is accountable for end-to-end disease-area translational science to inform therapy area and program-level biomarker strategies (from preclinical to launch) to increase the probability of success from preclinical to clinical transitions and enable earlier and higher-confidence asset-related decisions. This includes generation of foundational data as well as disease biomarker development and validation that allow timely deployment of tools/biomarkers to support Proof of Mechanism (PoM), signs of clinical efficacy, Proof of Concept (PoC), and pairing Mechanisms of Action (MoAs) with patient subtypes to predict responder populations. We are looking for a dynamic individual to excel in the following responsibilities.
Key Responsibilities
* Disease Biomarker Strategy Development and Delivery: Partner with Clinical Teams, Research Technologies and the Development organization with focus on the Respiratory portfolio to identify, establish biomarkers for decision making throughout clinical development phases and aligned with overall R&D goals. This includes identification, prioritization and validation of disease-relevant biomarkers, mechanistic/surrogate biomarkers, patient stratification, and differentiated response prediction, and their deployment into clinical studies with interpretation of data/results.
* Translational Leadership: Provide strategic leadership contributing to deep understanding of disease areas enabling development and execution of translational research strategies to support discovery and development of novel therapeutics, including evaluation and diligence of business development opportunities.
* Translational Innovation: Evaluate novel techniques and technologies (e.g., spatial transcriptomics) to inform translational initiatives, biomarker development and validation in collaboration with platform teams within a multi-functional matrix environment. Identify and guide validation of human assays (cells, tissues and organs) to enhance human translation and predictive value through resources such as the Human Cell Atlas, disease tissue multi-omics data and genetic resources (external or proprietary).
* Cross-functional Collaboration: Collaborate with Translational, Disease Teams, Human Genetics & Genomics, biology groups, biomarker platforms, Medicine Development Teams, HBSM, data-sciences, regulatory affairs, business development and commercial to ensure seamless integration of translational research and biomarker strategies across the drug development lifecycle.
* External Partnerships: Establish and maintain strategic collaborations with academic institutions, CROs, and other external partners to access cutting-edge technologies, tools, reagents, biosamples, biomarker expertise, and research capabilities. Foster a network of external experts and key opinion leaders to stay at the forefront of translational science and biomarker advancements. Contribute to evaluation and diligence of business development opportunities.
* Matrix Leadership: Provide mentorship, guidance, and professional development opportunities to ensure a high-performing and motivated team. Manage disease and project-level resources, budgets, and timelines to ensure successful execution of projects and achievement of milestones and RIITU objectives. Represent RIITU at portfolio governance reviews, providing input to pipeline and investment decisions.
Working Model
This role is based in the United Kingdom or the United States and follows a hybrid working model. You will be expected to work on-site regularly to collaborate with your team and partners.
How to Apply
If this role inspires you, please apply with your CV and a short cover note describing a recent translational achievement. Tell us what you did, why it mattered, and the impact it had. We welcome people from all backgrounds and value inclusion in how we hire and lead.
Compensation and Benefits
Salary ranges are location dependent. If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges from $189,750 to $316,250. The US salary ranges reflect location, skills, experience, and market rates. This position offers an annual bonus and eligibility for our long-term incentive program. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed for a country, the compensation will be discussed during recruitment.
Why GSK?
Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases to impact health at scale.
GSK is an Equal Opportunity Employer. We are committed to equal opportunity for all qualified applicants regardless of race, color, religion, sex, pregnancy, gender identity, sexual orientation, parental status, national origin, age, disability, genetic information, military service, or any basis prohibited by law.
We support flexible and agile working; discuss any adjustments needed during the recruitment process. For adjustments, contact UKRecruitment.Adjustments@gsk.com. See the Recruitment FAQ guide via the provided link for common questions.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses or employment agencies without prior written authorization from GSK’s commercial and HR department. This ensures compliance with relevant policies. If you are a US Licensed Healthcare Professional, GSK may report certain expenses as required by law.
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