Description We are currently looking for a Senior Benefit Risk Evaluation Assessor – Musculoskeletal, Trauma and Cosmetic to join our Benefit/Risk Evaluation Team II Function within the Safety and Surveillance group. This is a full-time opportunity, on a permanent basis. The role will be based in 10 South Colonnade, Canary Wharf London, E14 4PU. Government departments and agencies are working towards implementing a minimum 60% attendance in office sites. We are currently implementing a flexible, hybrid way of working, with a minimum of 8 days per month working on site to enable the collaboration and contact with partners and stakeholders needed to deliver MHRA business. Attendance on site is driven by business needs so depending on the nature of the role, this can flex up to 12 days a month, with the remainder of time worked either remotely or in the office. Some roles will need to be on site more regularly. Who are we? The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research. The Safety and Surveillance Group brings together into a single integrated structure devices and medicines safety expertise with enforcement capabilities. These functions will be supported by our data and evidence generating capabilities complementing our signal generating capabilities produced via the new Safety Connect System. The Musculoskeletal, Trauma and Cosmetic Benefit Risk Evaluation team monitors the safety of medicines and medical devices across these therapy areas. This includes a large focus on medical devices used for orthopaedics such as hip and knee joint replacements, cosmetic and plastic devices such as breast implants and wound care products used in the trauma context. The team cover medicines such as botulism toxin used for some cosmetic purposes, musculoskeletal gene therapy and creams and ointments used in wound care. What’s the role? The core purpose of this role is to provide a robust benefit risk assessment of potential safety signals within the Musculoskeletal, Trauma and Cosmetic therapeutic area using data from a range of sources and technical, scientific, clinical and regulatory knowledge and/or practical experience. Benefit risk assessors are responsible for engaging with a range of stakeholders including patients and the public to make timely and robust benefit-risk assessments and recommend safety actions and risk mitigations that are outcome focused. Whilst the focus of this role will be in medical devices there will be opportunities to work across both medicines and medical devices. The Benefit risk assessor will help deliver on our ongoing work and increase capacity to respond to new-emerging safety issues. They will have comprehensive medical device regulatory experience as well as professional, technical or scientific expertise in the Musculoskeletal, Trauma and Cosmetic therapeutic area. The experience of the successful applicant will be vital in helping to support new members of the team build their competencies. Key responsibilities: Lead, influence or deliver consistently high-quality critical appraisals/assessment projects for significant safety or risk:benefit issues evaluating all relevant information sources including real-world evidence in accordance with agreed timelines, seeking expert advice where needed and ensuring the patient experience is duly considered Actively engage with patients and the public, key external stakeholders, government departments, professional bodies and the wider health sector Develop communications for the public, senior officials or ministers as required and provide scientific, technical and clinical input to ensure regular and timely advice is communicated to healthcare professionals Lead and develop cross portfolio projects identifying and deploying resources and mentoring more junior staff as required to achieve agency patient safety goals Who are we looking for? Our successful candidate will: Have comprehensive experience in critically analysing clinical/scientific information from a range of sources including case reports, registries, clinical trials/investigations, and observational studies, making sound judgements for recommendations to protect patient safety and public health. Have in depth knowledge and experience of relevant regulations and procedures applicable medical devices. Have previous therapeutic and/or technical experience and expertise relevant to the work of the Musculoskeletal, Trauma and Cosmetic Benefit-Risk Evaluation team Have excellent interpersonal skills to facilitate team-working/team-leading, consulting and co-operating with colleagues from different disciplines and with variable degrees of expertise Share knowledge to improve the capability of the team, benefit risk evaluation group and the wider safety and surveillance function Person Specification: Method of assessment: A=Application, I=Interview, P=Presentation Behaviour Criteria: Making Effective Decisions (A, I) Delivering at Pace (A, I) Communicating and Influencing (A, I, P) Working Together (A, I, P) Experience Criteria: Excellent written communication skills, including the ability to write authoritative reports. Excellent verbal and presentation skills (A, I, P) Excellent interpersonal skills to facilitate team-working/team-leading, consulting and co-operating with colleagues from different disciplines and with variable degrees of expertise. (A, I, P) Comprehensive experience of relevant regulations and procedures applicable to medical devices. (A, I, P) Previous therapeutic and/or technical knowledge and experience relevant to the work of the Musculoskeletal, Trauma and Cosmetic Benefit-Risk Evaluation team, and sharing knowledge to improve the capability of the team. ( A, I) Comprehensive experience in critically analysing clinical/scientific information from a range of sources including case reports, registries, clinical trials/investigations, and observational studies, make sound judgements for recommendations to protect patient safety and public health. (A, I) Technical Criteria: A degree in a relevant health, scientific or engineering discipline e.g. medicine, biochemistry, physiology, medical engineering or regulation. (A) In depth knowledge of medical device regulations and the MHRA role in Benefit Risk Evaluation. (A, I) In depth specialist knowledge of medical products in the musculoskeletal, trauma and cosmetic therapeutic area. Previous experience of assessment focused work with orthopedic, breast and other cosmetic implants is highly advantageous. (A, I) Strengths Criteria: Analytical (I) Decisive (I) Catalyst (I) If you would like to find out more about this fantastic opportunity, please read our Job Description and Person Specification! Please note: The job description may not open in some internet browsers. Please use Chrome or Microsoft Edge. If you have any issue viewing the job description, please contact careers@mhra.gov.uk The selection process: We use the Civil Service Success Profiles to assess our candidates, find out more here. Online application form, including questions based on the Behaviour, Experience and Technical Success Profiles. Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application. Presentation, to be prepared as part of your interview, with further information being supplied when you reach this stage. Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles. In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of Previous therapeutic and/or technical knowledge and experience relevant to the work of the Musculoskeletal, Trauma and Cosmetic Benefit-Risk Evaluation team, and sharing knowledge to improve the capability of the team. Applicants are assessed on whether they meet any mandatory requirements as well as the necessary skills and experience for the role. Applications are scored based on the competency-based answers provided- ensure you have read these thoroughly and allow sufficient time. You can view the competencies for this role in the job description. Use of AI in Job Applications Artificial Intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our candidate guidance for more information on appropriate and inappropriate use. If you require any disability related adjustments at any point during the process, please contact careers@mhra.gov.uk as soon as possible. Closing date: 22 February 2026 Shortlisting date: 02 March 2026 Interview date: w/c 16 March 2026 Candidates will be contacted within a week of the sift and the interviews completed to inform them of the outcome. If you need assistance applying for this role or have any other questions, please contact careers@mhra.gov.uk Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules. Further information on whether you are able to apply is available here. Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must complete basic personnel security standard checks. Certain roles within the MHRA will require post holders to have vaccinations, and in some circumstances, routine health surveillance. These roles include: Laboratory-based roles working directly with known pathogens Maintenance roles, particularly those required to work in laboratory settings Roles that involve visiting other establishments where vaccination is required Roles required to travel overseas where specific vaccination may be required. Applicants who are successful at interview will be, as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicant’s details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government. Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility here. Individuals appointed on level transfer will retain their existing salary and are responsible for ensuring they fully understand the financial implications of any potential move and the impact (if any) on their terms. If an individual is in any doubt, they should seek clarification before accepting a job offer. Staff joining on promotion will receive up to a 10% increase of their current basic salary, or the pay band minimum, whichever is the greater. The individual will not retain any allowances paid by the former department/Agency, unless there are special circumstances, such as a reserved right to those allowances on transfer. Successful candidates may be subject to annual Occupational Health reviews dependent on role requirements. If you have any queries, please contact careers@mhra.gov.uk. In accordance with the Civil Service Commissioners’ Recruitment Principles our recruitment and selection processes are underpinned by the requirement of selection for appointment on the basis of merit by a fair and open competition. If you feel your application has not been treated in accordance with the Recruitment Principles and you wish to make a complaint, in the first instance, you should contact the MHRA Recruitment Team at careers@mhra.gov.uk. If you are not satisfied with the response you receive, you can contact the Civil Service Commission at: civilservicecommission.independent.gov.uk info@csc.gov.uk Civil Service Commission Room G/8 1 Horse Guards Road London SW1A 2HQ