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Bioprocess technical lead

Newport (Newport)
The BBI Group
Posted: 21 August
Offer description

BBI exists to help our customers create advances that improve health and save lives. We are seeking a Bioprocess Technical Lead to join our team. This is a fixed-term, full-time position based at our site in Freiburg. Join our team: advancing health, together.


The Role

Bioprocess Technical Lead will provide technical input throughout the early stages of design review and in particular bioprocess optimization, scale up and transfer strategy for recombinant protein expression at the CoE Recombinant Protein Expression and Purification. They will support the technical inputs that drive us to successful design reviews and subsequent successful scale ups with appropriate studies for the NPD roadmap using bioreactors from pilot scale to production scale of microbially/ mammalian produced recombinant proteins. The candidate will be responsible for supporting the different value streams in collaboration with strategic customers and the wider recombinant stakeholders where necessary to support delivery of overall recombinant portfolio for the business.

In this role your responsibilities will include:

1. Provide SME support for the projects involving troubleshooting through design review process and complex bioprocess scale up and downstream recovery of recombinant bacteria and yeasts. Essential
2. Thorough understanding on biological processes, geometric factors and mathematical models involved with scale up. Essential
3. In-depth knowledge in operation and maintenance of glass and SS bioreactors at small scale and manufacturing scale (1L up to 250L). Essential
4. Demonstrated experience in driving optimization of existing processes to improve efficiency, reduce costs, problem-solving pertaining scale-up of fermentation processes from lab scale to large scale.
5. Proficiency in using bioprocessing software and simulation tools with ability to oversee and support within the operational area where necessary.
6. Ability to advise on preparation of technology transfer documentation and technical communication of outsourcing of scale up activities to aid in OEM manufacture.
7. Knowledge on recovery/ purification of proteins expression systems for enzymes, antigens and antibodies with varying degrees of complexity.


You should apply if:
8. Experienced leader with a degree in microbiology, molecular biology, biotechnology, chemical engineering (related subjects may also be acceptable)
9. Master’s level
10. Experience in Life Science industry
11. Microbiology, Biotechnology, Biochemistry, Chemical engineering
12. Fermentation technologies for proteins, including antigens and enzymes
13. Ability to author SOP’s/ reports
14. Bioprocess optimization, scale up and transfer to regular production
15. Experience with different systems
16. Essential: E. coli, Other bacterial species and Yeasts
17. Desirable: Mammalian CHO and HEK
18. Recombinant protein services
19. Operation and maintenance of glass and SS bioreactors

Our Recruitment Process

If this role sounds like it’s for you, click ‘apply’ today. Once we’ve received your application, a member of our recruitment team will be in touch to arrange a call. On this call, we’ll be able to tell you a lot more about working here at BBI Solutions, how ‘a day in the life’ of this position looks and discuss the next stages of the recruitment process.

If you are an internal employee applying for this vacancy you and your manager are required to complete an internal transfer form. This needs to be completed in full and attached to your application along with your CV and cover letter.

As part of career development and succession planning internal applicants will receive priority consideration initially, please ensure that you apply within the initial two-week period to support this.


Why Choose BBI

We are committed to promoting and protecting the physical, financial, and emotional well-being of all our employees. With our employees focused on others, we’re focused on them. That’s why, at BBI, we’re dedicated to providing our employees with access to global resources and site-specific benefits that support their health and wellbeing.
20. Competitive Salary with Yearly Salary Reviews
21. 5% Contributory Pension Scheme
22. Life Assurance (4x Annual Salary)
23. Private Health Care Scheme – including dental
24. Global Employee Wellbeing Programme
25. Reward and Recognition Programme
26. Commitment to Career Development
27. Generous Annual Leave Package
28. Cycle to Work Scheme
29. Refer A Friend Scheme
30. Subsidised Canteen
31. Free Onsite Parking
32. Electrical Vehicle Lease Scheme
33. Electrical Charging Points
34. State of the Art Facilities – Certified Centres of Excellence

We’re also focused on development, creating an environment that allows our employees to nurture their talent and empowers you to make a difference. This is achieved by providing our employees with access to learning opportunities to help achieve personal career goals.

About BBI

For more than 70 years, we’ve been perfecting reagents, both native and recombinant, to help IVD and life-science teams turn breakthrough ideas into reliable, life-saving advances.

Great products are only the start. From troubleshooting tricky performance issues and customising reagents to meeting new regulatory standards, our scientists work to clear obstacles and accelerate progress. That’s why we continue to invest millions in new recombinant capabilities that help create diagnostics that improve health and save lives - in a more ethical and sustainable way than ever before.


Equal Opportunities
BBI are an equal opportunity employer and believe in fair treatment for all candidates. Qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.

We ask that all applicants complete an equal opportunity monitoring form on a voluntary basis, with all submissions remaining anonymous. The information on the form will be used for monitoring purposes only and will not be used in any decision affecting you.

Stay in Touch

To stay up to date with BBI’s global activities, take a look at our Facebook, X and LinkedIn pages. Click follow to receive the most up to date job and event information.


Please note that we reserve the right to close this advertisement at any time upon securing a suitable candidate.

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