Overview
The Principal Scientist I (Mass Spectrometry) aids in driving strategic scientific growth within our mass spectrometry group by leading high-impact value‑creation initiatives, mentoring junior staff, and expanding in-house capabilities. You will support business development through scientific proposal writing, client interactions, and by serving as a subject-matter expert on advanced bioanalytical assays with predominantly LC‑MS endpoints. Your leadership will champion scientific excellence, reinforce GxP compliance, and elevate our CRO’s reputation via publications, workshops, and cross-functional collaborations.
Responsibilities
Business Development & Scientific Strategy
* Collaborate with BD teams to develop scientific content for proposals, drive technical discussions with clients, and cultivate long-term relationships.
* Identify emerging industry needs and oversee Value Creation Projects (VCPs) and advance in-house capabilities to expand our assay portfolio.
* Lead feasibility studies and perform/oversee method development for the complex bioanalytical assays requested by our clients (including small molecules, large molecules, and new modalities at all stages of the development cycle).
* Lead transfer of the methods to study delivery group for validation and sample analysis, and monitor study progress as the methods are employed.
* Serve as the SME for complex bioanalytical assays (scientific rationale, sample preparation, chromatography, mass spectrometry, hybrid applications, troubleshooting, etc.).
* Mentor and train junior and mid-level scientists on advanced assay design, troubleshooting, data analysis, regulatory requirements and GxP documentation.
* Delegate responsibilities and review deliverables to ensure scientific rigor, data integrity, and on-time delivery.
Scientific Excellence & External Engagement
* Drive continuous improvement through internal audits, protocol enhancements, and corrective-preventive action initiatives.
* Represent the company at scientific conferences, workshops, and in peer-reviewed publications to showcase our capabilities and thought leadership.
Qualifications & Experience
* PhD in Chemistry, Biochemistry, Biology or related discipline with ≥2 years’ industry experience OR MSc/BSc in a relevant field with ≥7 years’ hands-on experience.
* Deep expertise in regulated bioanalytical environments (GLP/GCP) and familiarity with ICH bioanalytical guidelines.
* Demonstrated track record leading/performing development of bioanalytical LC‑MS assays for PK and/or PD applications in biological fluids and tissues using triple quadrupole instruments.
* Excellent leadership, project management, and cross-functional collaboration skills.
* Proven experience in business-facing roles: proposal writing, client presentations, and technical negotiations.
* Strong written and verbal communication skills in English.
Preferred Skills & Experience
* Experience in the bioanalytical quantitation of large molecules and new modalities using LC-MS
* History of leading or co-authoring peer-reviewed publications or patents in bioanalysis.
* Performed role of Study Director/ Principal Investigator/ Responsible Scientist in the support of regulatory studies.
* Bioanalytical CRO experience.
* Experienced user of high-resolution mass spectrometers.
* Experience of interactions with health authorities (FDA, EMA, MHRA).
PLEASE ENSURE THAT YOUR CV/RESUME IS SUBMITTED IN ENGLISH.
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