Company description:
OXB is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, OXB has more than 30 years of experience in viral vectors, the driving force behind the majority of gene therapies.
Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patients cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).
OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.
Job description:
Join Us in Changing Lives
AtOXB, our people are at the heart of everything we do. Were on a mission to enable life-changing therapies to reach patients around the worldand were looking for passionate individuals who embody our core values every day:Responsible, Responsive, Resilient, and Respectful.
Were currently recruiting for Biotechnologists at different levelsto join our Manufacturing team. In this role, you will be manufacturing commercial and clinical grade viral vector batches within a GMP cleanroom facility, playing a key part in advancing our mission and making a real difference.
Your responsibilities in this role would be:
* Upstream adherent and/or suspension mammalian cell culture, transfection and harvest of viral vector products
* Downstream processing including clarification, chromatography, ultra/diafiltration and fill/finish activities
* Ensuring batch success by working using good aseptic techniques
* Preparing, cleaning and maintaining the GMP facility including performing viable and non-viable environmental monitoring
* Preparing growth media and stock solutions using portable mixing tanks
* Completing Batch Manufacturing Records in a timely fashion throughout the manufacturing process
* Taking part in continuous improvement initiatives & development of production processes
* Investigating quality incidents, deviations and improving procedures
* Working to high standardsof health & safety
We are looking for:
* Flexibility to work shifts including early mornings, late nights and weekends when required
* Degree level qualification or equivalent experience
* Working within a GMP manufacturing or aseptic environment is advantageous but not essential
* Self-motivated with a strong focus on safety, quality, details, and results
* Good problem solving, interpersonal communication and team skills
* Excellent writing skills and computer literacy
About Us:
OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies.
OXB collaborates with some of the worlds most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturingexpertisein lentivirus, adeno-associated virus (AAV)and adenoviral vectors. OXBs world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatoryexpertise.
Why Join Us?
* ???Competitive total reward packages
* ???Wellbeing programmes?that support your mental and physical health
* ???Career development opportunities?to help you grow and thrive
* ???Supportive, inclusive, and collaborative culture
* ???State-of-the-art labs and manufacturing facilities
* ??A company that lives its values:?Responsible, Responsive, Resilient, Respect
We want you to feel inspired every day. AtOXB,werefuture-focused and growing fast. We succeed togetherthrough passion, commitment, and teamwork.
Ready to Make a Difference?
Collaborate. Contribute. Change lives.
#LI-RB1
We offer:
Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.
Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patients cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).
Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.
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