Senior Scientist (Protein Sciences - Small Molecule)
Location: CRUK Scotland Institute, Glasgow (Lab Based). Contract: Permanent, full time 35 hours per week. Salary: £41,700 – £51,300 plus benefits. Closing date: Friday 1st May 2026.
Key Responsibilities
* Expression and purification of recombinant proteins using bacterial and insect cell systems to support screening and crystallography programmes.
* Ensure all production is thoroughly characterised and QC’d using appropriate biochemical and biophysical methods.
* Interpret, analyse and summarise data clearly for presentation to varied audiences.
* Work collaboratively within multidisciplinary research teams.
* Communicate effectively, demonstrating openness and respect for others’ perspectives.
* Prioritise workload according to project objectives and deliver results on time.
* Drive scientific and technical innovation, including internal and external collaborations, staying current with developments in the field.
* Maintain accurate, up‑to‑date electronic laboratory notebook records.
* Take responsibility for assigned laboratory equipment and associated duties.
* Uphold safe, compliant and effective working practices.
Qualifications
* PhD or equivalent in Molecular Sciences, Protein Sciences, Chemistry or significant experience within a drug discovery environment.
* Significant experience in protein production and molecular biology to enable drug discovery projects.
* Ability to work in a fast‑paced, quickly changing environment, showing agility/flexibility to meet deadlines and goals with a can‑do attitude.
* Proficiency in current molecular biology techniques (PCR, cloning) to construct expression vectors and isolate genes.
* Experience in purification of tagged and native proteins via manual, AKTA and automated platforms using chromatographic techniques.
* Knowledge of protein analytical techniques (protein quantitation assays, SDS‑PAGE, HPLC, Western blotting, protein modifications such as biotinylation).
* A track record of delivering results across a diverse project portfolio by leading and driving strategic and scientific initiatives.
Benefits
We provide a generous benefits package, a wide range of career and personal development opportunities, high‑quality tools, and policies designed to support work‑life balance and wellbeing.
Equality, Diversity and Inclusion
We actively encourage applications from people of all backgrounds and cultures, particularly those from ethnic minority backgrounds who are currently under‑represented. We do not recruit anyone below the age of 18 in order to protect young people from health & safety and safeguarding risks. Adjustments can be made to enable all candidates to achieve fair and objective assessment.
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