Medical Director - Neurodegenerative Diseases (Alzheimer's Disease)
Contract | Outside IR35
Hybrid - 2 days per week onsite (Welwyn Garden City area)
The Opportunity
An innovative global biopharmaceutical organisation is seeking an experienced Medical Director - Neurodegenerative Diseases to support late-stage clinical development programmes in CNS, with a primary focus on Alzheimer's disease.
This role offers the opportunity to contribute to pivotal Phase III programmes aimed at addressing significant unmet medical needs in neurodegeneration. You will play a central role in translating cutting-edge science into high-impact clinical strategies, helping to bring potentially transformative therapies to patients.
This is a high-visibility, cross-functional leadership position within a global matrix environment.
Key Responsibilities
Support the design and execution of global clinical development strategies across all phases, with strong emphasis on Phase III programmes
Provide medical monitoring for ongoing interventional clinical trials
Contribute to protocol development, study design, and data interpretation
Partner closely with cross-functional teams including Clinical Operations, Safety, Biostatistics, Regulatory Affairs, Clinical Pharmacology, Biomarkers, and Research
Support preparation for regulatory interactions and health authority engagements
Participate in advisory boards and engage with external investigators and key opinion leaders
Translate clinical data into strategic development decisions
Candidate Profile
Essential
MD or MD/PhD (medical degree required)
Minimum 5 years' experience in longitudinal clinical research, including hands-on clinical trial experience (industry or academic setting)
Strong experience supporting or leading Phase II-III development programmes, with particular focus on Phase III
Experience in medical monitoring of interventional studies
Proven ability to work effectively within global, cross-functional matrix teams
Experience interfacing with regulatory authorities and external stakeholders
Excellent written and verbal scientific communication skills
Desirable
Direct experience in neurodegenerative diseases, particularly Alzheimer's disease
Experience designing late-stage CNS development strategies
Prior experience within a global pharmaceutical or biotechnology organisation
Involvement in regulatory submissions
Peer-reviewed publications in neurology or neurodegeneration
Who This Role Would Suit
We are seeking a medically trained physician who:
Brings strong late-stage CNS clinical development expertise
Is confident in medical monitoring and protocol design
Operates effectively in a complex, global matrix structure
Is comfortable engaging with regulators and external experts
Combines scientific rigour with strategic thinking
Work Arrangement & Contract Details
Contract position
Outside IR35
Hybrid working: 2 days per week onsite in the Welwyn Garden City area
If you are passionate about advancing innovation in neurodegenerative disease and want to contribute to high-impact late-stage programmes, we encourage you to apply.