Senior Scientist Upstream Development
The Company Glen Clova Scientific Ltd (GCS) is developing a new generation of Active Biologics to treat inflammatory conditions. We are an ambitious spinout from the University of Dundee aiming to address the global need to make effective treatments available for millions of patients. Our novel Virus-Like-Particle technology is poised to address inherent limitations of the current blockbuster class of Biologic drugs. Our vision is to make high end biotech pharmaceuticals much more accessible to patients than current blockbusters. If you aspire not only to be at the core of biotech innovation but also to tackle the global problem of high-cost medicine, this is a rare opportunity to join a highly dynamic team. Summary Job Title: Senior Scientist Upstream Development Location: Dundee Salary: £40,000 – £50,000 Contract Type: Full-time, permanent Job Description You will work in a team of fellow scientists and technicians, directly reporting to the CSO. You will be responsible for developing lab scale Upstream Process for our candidate prototype drugs expressed in E.coli. As and when required, you will also perform process development on other platforms (mammalian or Baculovirus or yeast/plant). You will carry out strain development, using external contractors for strain engineering, implement lab scale fermentation, and develop processes in close communication with fellow scientists implementing DSP. In your work, you will supervise a technician tasked to assist with assay delivery. You will also draft protocols for and coordinate in vivo assays to be performed by external service providers and liaise with external providers of specialized technologies (e.g. CD-spectra, EM). Pending overall workload requirements, you will also be asked to perform tasks associated with recombinant protein expression and purification. Experience and Qualifications You hold a PhD in a Biomedical subject. You have experience in Upstream Process Development. Industry experience is desirable. Key Requirements
* Practical experience in Upstream Development, in particular the ability to understand, design, and screen components for optimization (clone and strain engineering will be outsourced but be supervised by you). Experience with prokaryote fermentation.
* Documented ability to work independently, to read pertinent literature and understand emerging technology developments.
* Team player personality and excellent troubleshooting skills.
* Excellent record keeping, writing, communication and presentation skills, including drafting of reports.
* Ability to work under pressure of milestone – driven timelines.
Locations Dundee is an up and coming Biotech centre in a fantastic setting: Multiple beaches are within easy reach; housing is highly affordable even in catchments of nationally top-performing independent and state schools; there is a multitude of child-care providers. Dundee is a large university centre with a multi-cultural scene and vibrant night life, an award-winning theatre playhouse, a variety of museums. Transport and connections are excellent: the stunning Scottish Highlands can be reached in 45 minutes; the cultural buzz, and global airport connectivity of Edinburgh is 1 hour by train in addition to direct rail links to Glasgow (90 minutes) and Aberdeen (60 minutes). Additional Benefits Relocation allowance Transport / Parking: Free on-site parking (or free car park pass); Holiday: 24 days plus Scottish public holidays Maternity Leave: after 1 year of employment: Company options after a qualifying period of employment Company bonus scheme entitlement after completion of a qualifying probation period Pension scheme: Employer contributions into a personal private pension plan as % of income
#J-18808-Ljbffr