Location: Great Abington, Cambridge CB21 6AD (Agile; approximately 2 days a week from our office)
Clinical Research Manager
The Clinical Research Manager will play a key role in advancing ARUK’s drug prioritisation activities as part of the Clinical Accelerator Programme. Working closely with the Senior Clinical Research Manager, this role will drive the identification, evaluation, and progression of high‑potential drug candidates toward clinical trials, delivering tangible impact for people affected by dementia.
Managing the planning and delivery of ARUK’s drug prioritisation activities, this position works collaboratively with external stakeholders and various departments across the organisation, including the wider Research, Fundraising, and Policy, Communications and Involvement Teams, to develop the programme and ensure successful delivery and measurable impact.
Drug Prioritisation Programme Delivery and Development
* Lead the identification of therapies suitable for prioritisation for clinical trials in Alzheimer’s and other types of dementia through literature searches and communication with the clinical research community and key external partners, with support from the Senior Clinical Research Manager.
* Lead the development and drafting of high‑quality scientific dossiers that directly inform prioritisation decisions and progression of drug candidates.
* Lead the translation of recommendations from external advisory panels into actionable next steps.
* Work with the Senior Clinical Research Manager and the Senior Clinical Programmes Operations Officer to plan drug prioritisation activities, including meeting logistics, panel engagement, feedback and to track and evaluate progress.
* Identify, evaluate, and drive forward high‑impact opportunities for drug prioritisation and clinical development in consultation with Partnerships, Evidence and Funding teams.
* Design and embed scalable processes to proactively monitor the global drug development landscape, utilising databases, conference intelligence, and literature to curate a dynamic intelligence log that tracks therapeutic candidates, development progress, and emerging opportunities across industry and academia.
Driving the Advancement of the Clinical Accelerator Programme
* Drive planning and implementation of new activities relevant to continually develop and advance the clinical research strategy.
* Collaborate in mapping the clinical research ecosystem, identifying gaps in research and recommending actions to address them.
* Keep abreast of developments and trends in dementia clinical research to influence ARUK's strategies and decisions.
* Support and continuously strengthen internal reporting mechanisms, ensuring timely, high‑quality updates to Senior Leadership and relevant boards.
* Work closely with the Research Involvement Manager to integrate best practices in involvement and co‑production to ensure research is relevant for and supported by people affected by dementia.
* Ensure effective information‑sharing across internal stakeholders to maximise the visibility, uptake and strategic use of Clinical Accelerator Programme outputs.
* Aid in the planning, production, and communication of clinical research‑related content with the ARUK Communications and Fundraising teams.
Strengthening Relationships with External Stakeholders
* Foster and nurture relationships with clinical leaders and research funders in the UK to build the profile of ARUK’s clinical research and accelerate research towards a cure.
* Work closely with our Research Partnerships Manager to maintain and build partnerships that further our clinical research objectives.
* Support the Senior Clinical Research Manager and Head of Clinical Research in enhancing ARUK’s external profile through active participation in meetings and collaborations with key stakeholders.
Knowledge, Skills and Experience Needed
* PhD in a relevant biomedical field or equivalent experience in clinical or scientific research.
* Strong ability to critically interpret and evaluate pre‑clinical and clinical data.
* Familiarity with the drug development process from pre‑clinical studies to regulatory approval.
* Demonstrable commitment to collaborative and inclusive working.
* Proven experience in project management with the ability to adhere to deadlines and prioritise tasks.
* Understanding of research programme management.
* Experience or understanding of preparing scientific dossiers or evidence summaries to inform research prioritisation, funding, or strategic decision‑making.
* Understanding of dementia research and funding landscapes.
* Experience working with biotech and pharmaceutical companies.
* Exceptional scientific communication skills (written and verbal).
* Detail oriented.
* Commitment to ARUK’s vision, mission and values.
* Values the involvement of people with lived experience in research.
* Highly self‑motivated with the ability to work across different teams and departments.
* Solution‑focused with the ability to problem‑solve creatively.
* Able to work independently.
* Collaborative approach with ability to build strong relationships with a range of stakeholders.
* Good communication skills with the ability to tailor communications to a range of audiences.
The closing date for applications is the 28th June 2026.
We value diversity and are committed to creating an inclusive culture where everyone can be themselves and reach their full potential. We actively encourage applications from people of all backgrounds and cultures, in particular those from ethnic minority backgrounds who are currently under‑represented. Any offer of employment is however subject to you having the right to work in the UK.
Alzheimer's Research UK is a registered charity, numbers 1077089 and SC042474.
3 Riverside, Granta Park, Cambridge CB21 6AD
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