We are seeking an outstanding researcher to join Professor Teuta Pilizota's group at the University of Cambridge, to investigate how physico-chemical forces influence bacterial growth and death. The project focuses on Vibrio natriegens, one of the fastest-growing organisms, which doubles approximately every 10 minutes. Despite its high proteome similarity (>97%) to V. campbellii, which grows more slowly, the reasons for its rapid growth are unclear. Our preliminary studies suggest that the cytoplasmic environment of V. natriegens may have unique physico-chemical properties that accelerate biochemical reactions.
The successful candidate will collaborate with an international HFSP-funded team (https://www.hfsp.org/sites/default/files/195x265Grant%20Award%20Booklet2024_7.pdf) to characterize factors such as pH, osmolytes, crowding, and membrane potential across various conditions. We aim to understand how these factors influence cell growth and death, particularly by comparing V. natriegens with V. campbellii and E. coli. This research will extend current molecular-focused studies to explore the cytoplasmic environment's role in cellular processes.
Appointment at the research associate level requires a PhD, including candidates who have submitted but not yet received their degree. In such cases, initial appointment will be at the research assistant level, with a subsequent upgrade upon PhD completion.
References will be required before interviews, so please provide your consent on the application form. Upload your CV and cover letter via the online application system. Only requested documents will be considered.
This is a fixed-term position with funding secured for 2 years, with potential extension depending on funding availability.
To apply, click the 'Apply' button to create an account and submit your application online. Informal inquiries can be directed to Professor Teuta Pilizota at tp579@cam.ac.uk. Please quote reference KA46259 in your application and correspondence.
The University promotes equality, diversity, and inclusion and encourages applications from all societal sections. Applicants must be eligible to live and work in the UK.
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