Senior Director Neurodegeneration, Translational Sciences
Location: United Kingdom or United States; on‑site required with flexibility for hybrid working arrangements.
Position Summary
Reporting to the Vice President of Translational Sciences, Respiratory, Immunology and Inflammation Translational Unit (RIITU), the Senior Director will lead translational initiatives in neurodegeneration, driving disease‑area biomarker strategies, single‑cell technology application and cross‑functional collaboration to accelerate therapeutic progress.
Responsibilities
* Provide strategic leadership advancing translational research strategies, including evaluation of business development opportunities.
* Evaluate and adopt novel technologies (e.g., spatial transcriptomics) to inform biomarker development.
* Lead human assay validation using cell, tissue, organ models and multi‑omics resources.
* Develop and execute disease biomarker strategies, partnering with Disease, Research, and Development teams.
* Collaborate with cross‑functional teams (Medicine Development, Regulatory Affairs, Biomarker Platforms, etc.) and integrate strategies across the drug development lifecycle.
* Establish and maintain external collaborations with academia, CROs, and other partners.
* Provide mentorship, manage resources and budgets, and represent RIITU in portfolio governance.
Basic Qualifications
* Ph.D. in a relevant discipline (Cell/Molecular Biology, Genetics, Pharmacology, etc.).
* Extensive expertise in neurodegenerative disease translational science and biomarker implementation.
* Proven experience in a pharmaceutical/biotech setting, with a broad knowledge of translational research technologies.
* Strong publication record and recognition as a biomarker/translational science expert.
* Experience in clinical trial setting, authorship and oversight of clinical/regulatory documents.
* Knowledge of regulatory requirements and industry standards for biomarker development and validation.
* Track record of program decision making via biomarker strategies that deliver insights for clinical transition milestones.
* Experience leading external collaborations and business‑development evaluations.
* Excellent people‑management skills and ability to prioritize multiple projects.
* Inclusive matrix leadership with ability to inspire teams.
* Strong problem‑solving and critical‑thinking abilities.
Preferred Qualifications
* Awareness of bioinformatics/computational methods supporting translational and biomarker data analysis.
Why GSK
Uniting science, technology and talent to get ahead of disease together. GSK is an equal‑opportunity employer and welcomes diverse applicants.
EEO Statement
GSK is an Equal Opportunity Employer. Employment will be decided solely on qualifications and not based on race, color, religion, sex, gender identity, sexual orientation, age, disability, genetic information, military service, or any other factor prohibited by law.
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